A 22 year old woman had signs of rheumatic mitral and aortic valve disease early In pregnancy. Cardiac catheterization was performed during her third month of pregnancy under two-dimensional echocardiographic control without the use of ionizing radiation. Severe mitral stenosis with mild aortic stenosis was found. Five cubic centimeters of 5 percent dextrose in water were injected by hand to obtain left ventriculograms and supravalvular aortograms of sufficient quality to diagnose valvular regurgitation. The use of "echo-catheterization" may have s@ificant advantages In selected clinical situations.There is a strong contraindication to the use of ionizing radiation during the early stages of pregnancy due to its known teratogenic effects [ 1 ] . Indeed, avoidance of ionizing radiation to the gonads is desirable for any woman in the reproductive age range. Young women with cardiac disease who become pregnant face a possible worsening of their hemodynamic functions later in pregnancy due to increased cardiac demands during the third trimester [2,3]. Thus, when a physician is asked to evaluate such a situation in order to decide if an operation will be necessary to prevent hemodynamic deterioration later in pregnancy, he is presented with a dilemma. Cardiac catheterization is frequently necessary to obtain precise information on which to base operative recommendation.When recently confronted with this problem we decided to attempt catheterization entirely under twodimensional echocardiographic control.
CASE REPORTA 22 year old woman was admitted to tha Thoraxcenter in the second month of pregnancy. During the year before examination she noted gradually increasing fatigue and dyspnea on exertion. She denied having orthopnea. palpitation or precordial pain; she was able to do har housework with difficulty and was judged to be in New York Heart Association Class Ill functional capacity. On physical examination the patient appeared healthy. Blood pressure was 100/60 mm Hg and pulse rate 100 beats/min and regular. The carotid upstroke was mildly slowed. There was a diastolic apical trill. The first heart sound was increased in intensity, the second was normal, followed by an opening snap and a loud diastolic rumble. There was a grade 316 ejection murmur at the upper right sternal border, and a soft early diastolic decrescendo murmur at the lower left sternal border. The liver was not enlarged, and there was no peripheral edema.The