Echocardiographic diagnosis of an infected myxoma in an atypical location

Bough, Edward W.; Johnson, Eric E.; Zacks, Sumner I.; Boden, William E.; Mandel, Alex; Medeiros, Atone A.; Korr, Kenneth S.; Shulman, Richard S.; Yashar, James J.

doi:10.1016/0002-8703(87)90071-8

Cited by 14 publications

(9 citation statements)

References 7 publications

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“…It is well known that the incidence of cerebral and systemic embolization from an infected myxoma is much higher (88% of cases) than that from uninfected myxoma (33% of cases) . This is caused by fragile fibrin thrombi attached to the infected myxoma, resembling vegetations in infective endocarditis.…”

Section: Discussionmentioning

confidence: 99%

Infected Cardiac Myxoma

Nagata¹,

Totsugawa²,

Katayama³

et al. 2013

J Card Surg

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A 66-year-old male presenting with low-grade fever and general fatigue was diagnosed as having infected myxoma of the left atrium. Blood cultures grew Streptococcus mitis. He underwent urgent resection and histological examination revealed tumor cells in a mucopolysaccharide matrix and bacterial colonies along with active inflammation. Infected cardiac myxoma is extremely rare; however, it contains a potential risk of arterial embolization and so early diagnosis and urgent surgery should be considered.

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Section: Discussionmentioning

confidence: 99%

Infected Cardiac Myxoma

Nagata¹,

Totsugawa²,

Katayama³

et al. 2013

J Card Surg

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“…However, once infected, according to Bough et al, the incidence of cerebral and systemic embolization from infected atrial myxoma is much higher (88% of cases) than those reported from uninfected myxoma (33% of cases) or uncomplicated endocarditis (40% of cases) [7]. In our review, cerebral complications including cerebral infarction, haemorrhage and brain abscess were reported in at least ten cases (16.4%) in the literature, and a systemic embolism including cerebral infarction were reported in at least 24 cases (39.3%).…”

Section: Discussionmentioning

confidence: 99%

Successful surgical resection of infected left atrial myxoma in a case complicated with disseminated intravascular coagulation and multiple cerebral infarctions: case report

Yoshioka

Takahashi

Ishizaka

et al. 2011

J Cardiothorac Surg

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Cardiac myxoma is the most common primary cardiac tumour, but infected cardiac myxoma is relatively rare. Infected cardiac myxoma is very fragile, and has a potential to lead to catastrophic disorder with systemic bacteremia, systemic mycotic embolism, and disseminated intravascular coagulation (DIC).We present here the successful surgical treatment of a case of infected left atrial myxoma with septic shock, DIC and cerebral infarction without hemorrahage. Collective review of 58 reported cases with infected cardiac myxoma revealed that surgical treatment for it were still challenging and its result was poor. Until date, only one successful surgical treatment for a case complicated by DIC and cerebral infarctions has been reported, and our report describes second such case of successful resection. Even though this report is limited to a case, only aggressive and prompt surgical intervention could relieve the intractable conditions in such a patient with extremely high risk.

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“…Nevertheless, even today, infected atrial myxomaremains quite difficultto diagnose in a clinical setting. It is well acknowledged that the complication of embolization of uninfected atrial myxomaitself is very common;nonetheless, once infected, the incidence of cerebral and systemic embolization from infected atrial myxomais much higher (88% of cases) than that from uninfected myxoma(33% of cases) or uncomplicated endocarditis (40% of cases) (8), because it is speculated that these vegetations are particularly unstable. Surgical excision is the only means of completely treating infected atrial myxomaand antibiotic therapy alone is not effective therapy.…”

Section: Discussionmentioning

confidence: 99%

Infected Left Atrial Myxoma.

et al. 2002

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A 47-year-old Japanese womanwith a continuing high fever was promptly diagnosed as having infected atrial myxomaone day after admission based on transthoracic echocardiographic findings and positivity for bacteria in blood culture. The mass was removed by an urgent open heart surgery. Histopathological examination confirmed that this mass was a myxoma with gram-positive bacterial colonies. Generally, antemortem diagnosis is difficult and there is a high mortality of patients with infected myxoma; however, this patient completely recovered from the illness because of the prompt diagnosis. This is the 37th case of definite infected myxomareported in the literature. The cause of infection of this patient might have been the acupuncture therapy she underwent for weight reduction. (Internal Medicine 41: 957-960, 2002)

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Echocardiographic diagnosis of an infected myxoma in an atypical location

Cited by 14 publications

References 7 publications

Infected Cardiac Myxoma

Infected Cardiac Myxoma

Successful surgical resection of infected left atrial myxoma in a case complicated with disseminated intravascular coagulation and multiple cerebral infarctions: case report

Infected Left Atrial Myxoma.

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