Echinacea purpurea (L.) Moench extract suppresses inflammation by inhibition of C3a/C3aR signaling pathway in TNBS-induced ulcerative colitis rats

Polyphenolic Characterization and Anti-Inflammatory Effect of In Vitro Digested Extracts of Echinacea purpurea L. Plant Parts in an Inflammatory Model of Human Colon Cells

“…Thus, despite several preclinical studies reporting anti-inflammatory activities for EP extracts derived from different parts or components of the plant and subjected to various extraction processes [17][18][19][20], there are no studies that have evaluated differences in the efficacy from the different parts of EP collected at the same time and subjected to same extraction process. Regarding intestinal-inflammatory diseases, to the best of our knowledge, only two in vivo studies have reported that the EP extracts exerted a potential protective effect by decreasing inflammation and oxidative stress in ulcerative colitis rat models [21,22]. Similarly, the anti-inflammatory activities of EP extracts and some of their main components, such as chicoric acid, have been mainly investigated in human-and mouse-derived immune cells and other systemic inflammatory models.…”

Effects of Plant Polysaccharides Combined with Boric Acid on Digestive Function, Immune Function, Harmful Gas and Heavy Metal Contents in Faeces of Fatteners

“…A total of 90 crossbred fatteners (Duroc × Landrace × Yorkshire, 90 days old, from the same farm origin) with an initial body weight (IBW) of 41.25 ± 3.07 kg, were evenly divided into five groups, three replicate pens per group and six fatteners per pen. The five treatment groups were as follows: the control group was fed with a basal diet without boric acid and plant polysaccharides (Con), the experimental group I was fed with a basal diet + 40 mg/kg of boric acid (BA) [ 16 ], the experimental group II was fed with a basal diet + 40 mg/kg of boric acid + 400 mg/kg of 50% Astragalus polysaccharides (BA+APS) [ 17 ]; the experimental group III was fed with a basal diet + 40 mg/kg of boric acid + 200 mg/kg of 70% Ganoderma lucidum polysaccharides (BA+GLP) [ 18 , 19 ]; the experimental group IV was fed with a basal diet + 40 mg/kg of boric acid + 500 mg/kg of 10% Echinacea polysaccharides (BA+EPS) [ 20 ]. The whole experiment lasted for 90 days.…”

Effects of Plant Polysaccharides Combined with Boric Acid on Digestive Function, Immune Function, and Harmful Gas and Heavy Metal Contents in Faeces of Finishing Pigs

“…Crossbred pigs were randomly assigned to five experimental groups, each replicate with 6 pigs and 3 replicates per group, and were fed by adding to the base ration as follows: Con) A control, in which animals received a basic feed; BA ) experimental group I, basic feed supplemented with 40 mg/kg of boric acid [19,20]; BA+APS) experimental group II , basic feed supplemented with 40 mg/kg of boric acid and 400 mg/kg of Astragalus polysaccharides [18,21]; BA+GLP) experimental group III, basic feed supplemented with 40 mg/kg of boric acid and 200 mg/kg of Ganoderma lucidum polysaccharides [22,23]; and BA+EPS) experimental group IV, basic feed supplemented with 40 mg/kg of boric acid and 500 mg/kg of Echinacea polysaccharides [24]. The amount of boric acid and polysaccharides added was determined according to the literature and pre-experimentation in this subject group.…”