Echinacea in the prevention of induced rhinovirus colds: A meta-analysis

Schoop, Roland; Klein, Peter; Suter, Andy; Johnston, Sebastian L.

doi:10.1016/j.clinthera.2006.02.001

Cited by 105 publications

(79 citation statements)

References 31 publications

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“…The chemical diversity these plants exhibit has made it difficult for researchers to determine if Echinacea can be effective in treating colds and other respiratory infections (6). Inconsistent results have been obtained from several placebocontrolled studies designed to determine whether Echinacea preparations were effective in the prevention of the common cold and other upper respiratory infections.…”

Section: Introductionmentioning

confidence: 96%

Echinacea Species and Alkamides Inhibit Prostaglandin E₂ Production in RAW264.7 Mouse Macrophage Cells

LaLone

Hammer

et al. 2007

J. Agric. Food Chem.

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Inhibition of prostaglandin E 2 (PGE 2 ) production in lipopolysaccharide-stimulated RAW264.7 mouse macrophage cells was assessed with an enzyme immunoassay following treatments with Echinacea extracts or synthesized alkamides. Results indicated that ethanol extracts diluted in media to a concentration of 15 μg/ mL from E. angustifolia, E. pallida, E. simulata, and E. sanguinea significantly inhibited PGE 2 production. In further studies, PGE 2 production was significantly reduced by all synthesized alkamides assayed at 50 μM, by Bauer alkamides 8, 12A analogue, and 14, Chen alkamide 2, and Chen alkamide 2 analogue at 25 μM and by Bauer alkamide 14 at 10 μM. Cytotoxicity did not play a role in the noted reduction of PGE 2 production in either the Echinacea extracts or synthesized alkamides. High-performance liquid chromatography analysis identified individual alkamides present at concentrations below 2.8 μM in the extracts from the six Echinacea species (15 μg/mL crude extract). Because active extracts contained 2, it is likely that alkamides may contribute toward the anti-inflammatory activity of Echinacea in a synergistic or additive manner.

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Section: Introductionmentioning

confidence: 96%

Echinacea Species and Alkamides Inhibit Prostaglandin E₂ Production in RAW264.7 Mouse Macrophage Cells

LaLone

Hammer

et al. 2007

J. Agric. Food Chem.

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“…Les polysaccharides de l'échinacée Echinacea purpurea, angustifolia [25,54], ainsi que les plantes adaptogènes comme le ginseng peuvent pallier cette faiblesse transitoire de l'immunité [60].…”

Section: Total : Pointsunclassified

The value of medicinal plants in smoking cessation

Gigon

2008

Phytothérapie

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“…In brief, the numerous randomized studies, systematic reviews and meta-analysis indicate that a likely benefit exists, albeit small, due to the pharmacological activity of Echinacea. [17][18][19] Unfortunately, certain controversy has been generated about these results. As Hart et al 20 discussed regarding the results obtained from three meta-analyses on the efficacy of Echinacea in the prevention and treatment of common cold, the methodology followed in a systematic review (search strategy, inclusion and exclusion criteria, data analysis, etc.)…”

Section: Assessment Of Pfs High and Low Intakesmentioning

confidence: 99%

Plant food supplement (PFS) market structure in EC Member States, methods and techniques for the assessment of individual PFS intake

et al. 2011

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The popularity of herbal products, especially plant food supplements (PFS) and herbal medicine is on the rise in Europe and other parts of the world, with increased use in the general population as well as among specific subgroups encompassing children, women or those suffering from diseases such as cancer. The aim of this paper is to examine the PFS market structures in European Community (EC) Member States as well as to examine issues addressing methodologies and consumption data relating to PFS use in Europe. A revision of recent reports on market data, trends and main distribution channels, in addition an example of the consumption of PFS in Spain, is presented. An overview of the methods and administration techniques used to assess individual food consumption as a starting point, including their uses and limitations, as well as some examples of studies that collect Food Supplement (FS) information, including herbal/botanical/plant-derived products are also discussed. Additionally, the intake estimation process of food nutrients is described and used to propose the PFS ingredients intake estimation process. Nationally representative PFS consumption data is scarce in Europe. The majority of studies have been conducted in Scandinavia and the UK. However the heterogeneity of definitions, study design and objectives make it difficult to compare results and extrapolate conclusions.

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Echinacea in the prevention of induced rhinovirus colds: A meta-analysis

Cited by 105 publications

References 31 publications

Echinacea Species and Alkamides Inhibit Prostaglandin E₂ Production in RAW264.7 Mouse Macrophage Cells

Echinacea Species and Alkamides Inhibit Prostaglandin E₂ Production in RAW264.7 Mouse Macrophage Cells

The value of medicinal plants in smoking cessation

Plant food supplement (PFS) market structure in EC Member States, methods and techniques for the assessment of individual PFS intake

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Echinacea in the prevention of induced rhinovirus colds: A meta-analysis

Cited by 105 publications

References 31 publications

Echinacea Species and Alkamides Inhibit Prostaglandin E2 Production in RAW264.7 Mouse Macrophage Cells

Echinacea Species and Alkamides Inhibit Prostaglandin E2 Production in RAW264.7 Mouse Macrophage Cells

The value of medicinal plants in smoking cessation

Plant food supplement (PFS) market structure in EC Member States, methods and techniques for the assessment of individual PFS intake

Contact Info

Product

Resources

About

Echinacea Species and Alkamides Inhibit Prostaglandin E₂ Production in RAW264.7 Mouse Macrophage Cells

Echinacea Species and Alkamides Inhibit Prostaglandin E₂ Production in RAW264.7 Mouse Macrophage Cells