eCG e densidade vascular em úteros bovinos

Pinto, Joana

doi:10.11606/d.10.2009.tde-09082010-111421

Cited by 1 publication

(1 citation statement)

References 90 publications

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“…A similar positive association between plasma Mn levels and consumption of dairy products has been observed among the general population by other authors [65]. This can be explained by Mn supplementation for cattle [66,67], a measure implemented in Portugal and in other countries due to its role in reproduction and cattle fetal development [68], which may increase the amount of Mn in cow's milk. It is important to emphasize that measures of Mn supplementation in cattle must be approached with caution, because urinary Mn levels found in pregnant women consuming at least two 250 mL cups of milk a day (2.39 µg/L) were above the Mn levels observed in pregnant women with pregnancy complications or with low weight newborns.…”

Section: Discussionsupporting

confidence: 75%

Essential Trace Elements Status in Portuguese Pregnant Women and Their Association with Maternal and Neonatal Outcomes: A Prospective Study from the IoMum Cohort

Bracchi,

Guimarães,

Rodrigues

et al. 2023

Biology

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Cobalt (Co), copper (Cu), manganese (Mn), molybdenum (Mo), and zinc (Zn) are essential trace elements (ETEs) and important cofactors for intermediary metabolism or redox balance. These ETEs are crucial during pregnancy, their role on specific pregnancy outcomes is largely unknown. This prospective study (#NCT04010708) aimed to assess urinary levels of these ETEs in pregnancy and to evaluate their association with pregnancy outcomes. First trimester pregnant women of Porto and Lisbon provided a random spot urine sample, and sociodemographic and lifestyle data. Clinical data were obtained from clinical records. Urinary ETEs were quantified by inductively coupled plasma mass spectrometry (ICP-MS). A total of 635 mother:child pairs were included. Having urinary Zn levels above the 50th percentile (P50) was an independent risk factor for pre-eclampsia (PE) (aOR [95% CI]: 5.350 [1.044–27.423], p = 0.044). Urinary Zn levels above the P50 decreased the risk of small for gestational age (SGA) birth head circumference (aOR [95% CI]: 0.315 [0.113–0.883], p = 0.028), but it increased the risk SGA length (aOR [95% CI]: 2.531 [1.057–6.062], p = 0.037). This study may provide valuable information for public health policies related to prenatal nutrition, while informing future efforts to de-fine urinary reference intervals for ETEs in pregnant women.

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