Ecdysteroids from Vitex Species: Distribution and Compilation of Their ¹³C‐NMR Spectral Data

Abstract

Iridoids and ecdysteroids are found in some genera of the family Verbenaceae. In such cases, they are used as chemotaxonomic markers for the difficult task of taxonomic identification by using morphological characteristics of plants belonging to this family. The present work describes the distribution of ecdysteroids in plants from the genus Vitex from a review of previous work on seventeen Vitex species. In addition, (13)C-NMR data of the main ecdysteroids found in this genus are described. This study attempted to summarize previous research on ecdysteroids distribution in Vitex species with the addition of (13)C-NMR analysis to further refine the characterization of these compounds in the Verbenaceae family.

Absolute Configuration and Docking Study of Canescensterone, a Potent Phytoecdysteroid, with Non‐Lepidopteran Ecdysteroid Receptor Selectivity

“…Interestingly, a literature search revealed that the side-chain configuration for a number of ecdysteroids, especially with two methylene groups in the side-chain, has only been assigned tentatively. [24,27] In the past, differences in chemical shifts were used to identify the configuration at C-24. [28] However, some ecdysteroids show negligible differences in their 13 C chemical shifts even though they represent epimers (e.g., 20,26-dihydroxyecdysone).…”

Volatile Metabolomic Composition of Vitex Species: Chemodiversity Insights and Acaricidal Activity

“…For both the chemical compound and genetic markers evaluated by clustering ( Figures 1 , 3 ), V. gardneriana was isolated from the other three species. This may be related to genotypic differences for this species, as it is found in a different biome ( Sena Filho et al, 2008 ) which may influence the expression of genes used for synthesis of chemical compounds. The use of two data tools (chemical and genetic diversity) more thoroughly supports systematic characterization of the species studied ( Rahalia et al, 2016 ), and validates our chemical marker proposal for the Vitex genus, namely, using the sesquiterpene skeleton with seven member rings as a biomarker candidate.…”

Pharmacological effects and molecular mechanisms of action of a herbal medicine based on Vitex agnus-castus

“…2). Структура и результат исследования показывают, что действие Мастодинона сравнимо с действием бромокриптина [7].…”