Eccrine porocarcinoma at unusual location

Supekar, BhagyashreeB; Tomar, SuyashS; Bhushan, Ravi; Mukhi, JayeshI; Singh, RajeshP; Bhat, Dharitri; Jaiswal, Abhisek

doi:10.4103/jdds.jdds_40_21

Cited by 1 publication

(2 citation statements)

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“…Moreover, to avoid misdiagnosis due to histological variations, immunohistochemical studies are typically performed using EMA, PAS, CKs (AE1/AE3), p63, and Ki67, all of which are positive in most porocarcinoma cases[ 6 , 8 ]. However, porocarcinomas can mimic SCC when they exhibit pagetoid intraepidermal spread, adnexal structure colonization, acantholysis, and pseudogland formation[ 9 ]. In such cases, ductal differentiation, intracytoplasmic lumina, and CD117 positivity can facilitate the differential diagnosis of SCC[ 2 , 3 , 9 ].…”

Section: Discussionmentioning

confidence: 99%

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Porocarcinoma in a palm reconstructed with a full thickness skin graft: A case report

Lim,

Kwon,

Kim

et al. 2024

World J Clin Cases

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BACKGROUND Porocarcinoma is a rare type of skin cancer that originates from sweat gland tumors. It is an aggressive malignant skin cancer that is difficult to diagnose clinically owing to its rarity and similarity to squamous cell carcinoma (SCC). CASE SUMMARY This case involved a 92-year-old woman, a farmer by profession, presented with an exophytic and verrucous mass on her left palm that had formed 2 years prior and caused chronic pain and frequent bleeding. Initially, the patient was diagnosed with SCC using a punch biopsy; however, a repeat biopsy with additional immunohistochemical tests was performed for porocarcinoma. Ultimately, the patient was diagnosed with porocarcinoma and reconstruction was planned using a full-thickness skin graft. After treatment, the range of motion of the palm was preserved, and the aesthetic outcome was favorable. At 6 mo of follow-up, the patient was satisfied with the outcome. CONCLUSION Porocarcinoma is commonly misdiagnosed as SCC; therefore, clinicians should consider porocarcinomas when evaluating mass-like lesions on the hands.

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Section: Discussionmentioning

confidence: 99%

“…However, porocarcinomas can mimic SCC when they exhibit pagetoid intraepidermal spread, adnexal structure colonization, acantholysis, and pseudogland formation[ 9 ]. In such cases, ductal differentiation, intracytoplasmic lumina, and CD117 positivity can facilitate the differential diagnosis of SCC[ 2 , 3 , 9 ].…”

Section: Discussionmentioning

confidence: 99%