Eccrine Porocarcinoma: A Case Report and Review of the Literature

Abstract

Eccrine porocarcinoma is a rare form of skin cancer that is often confused with other types of skin malignancy. The present paper highlights a typical case to remind plastic surgeons of the natural history, pathological findings and current literature on the management of this cancer.

Porocarcinoma: A systematic review of literature with a single case report

“…[10] Among reported cases, 8th decade of life is the ideal age of affection followed by 7th decade (Table 1). [1], [3], [6], [10], [11], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34] EP does not have predilection for specific part of the body. [24] Arslan et al stated that it tends to involve most frequently in the extremities especially lower limbs, followed by trunk and head while current literature review showed that EP occurs most commonly at the lower limbs (35%) followed by head(24%) and upper limbs (14%) (Table 2).…”

“…[2], [3], [13], [11], [16], [17], [19], [23], [25], [27], [28], [31], [32] EP occurs as a single mass or nodule in 72% of the cases, ulceration (26%), and as a discharging sinus in 2% of cases. [1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36] Although the pre-invasive markers and the pathogenesis of EP are not clear, according to some papers, risk factors include exposure of the affected area to trauma, burning, or radiotherapy, immunosuppressive drugs especially after organ transplantation, prolonged exposure to ultraviolet light and AIDS. [10] The gross examination is an important part of the assessment.…”

Eccrine porocarcinoma arising from the knee

“…Benign eccrine porocarcinoma arises from within eccrine gland ducts in the epidermis. Malignant transformation is rare, but should be suspected when bleeding occurs [1]. Malignant eccrine porocarcinoma was suspected in the present patient due to the malignant histology in specimens from the right knee skin lesion and examination of the completely resected primary tumor.…”

Eccrine Porocarcinoma on an Unusual Location

“…Lenf nodü tutulumu varsa lenf nodü diseksiyonu gereklidir. Lenf nodü tutulumunun olduğu olgularda mortalite %67 olarak bildirilmiştir (10). Ekrin porokarsinomda sentinel lenf nodü diskesiyonun rolü henüz kesin olarak bilinmemektedir (9,10).…”