Eccrine Anhidrosis Due to Glutaraldehyde, Formaldehyde, and Iontophoresis**From the Division of Dermatology, Department of Medicine, University of California School of Medicine, San Francisco, California 94122.

Gordon, Bernard I.; Maibach, Howard

doi:10.1038/jid.1969.171

Cited by 38 publications

(2 citation statements)

References 5 publications

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“…The reaction is complex and differs from the reversible type of Schiff base complex which occurs between ordinary aldehydes and simple amine groupings. Glutaraldehyde produces anhidrosis by combining with the keratin wall of the sweat duct to give poral closure (Gordon and Maibach, 1964; Sato and Dobson, 1969).…”

Section: Discussionmentioning

confidence: 99%

The treatment of viral warts with glutaraldehyde

Allenby

1977

Int J Clinical Practice

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Section: Discussionmentioning

confidence: 99%

The treatment of viral warts with glutaraldehyde

Allenby

1977

Int J Clinical Practice

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“…Während eine 10%ige wäßrige Lösung im Bereich der Fußsohlen vertragen wurde, bewirkten 5 %ige Lösungen Reizerscheinungen an dünneren Hautstellen. 1-2 %ige Lösungen wurden insbesondere bei offener Applikation auf der intakten Haut reaktionslos vertragen (Gordon and Maibach 1969;Juhlin and Hansson 1968;Reifenrath et al 1985). Zur genaueren Bestimmung der Haut-Reizschwelle im Rahmen des in Kapitel 4.4.1 aufgeführten Sensibilisierungstests wurden freiwilligen Versuchspersonen Konzentrationen von 0,1; 0,2 und 0,5 % Glutardialdehyd im okklusiven Epikutantest appliziert.…”

Section: Wirkung Auf Haut Und Schleimhäuteunclassified

Glutardialdehyd [MAK Value Documentation in German language, 2006]

2012

The MAK‐Collection for Occupational Health and Safety

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Veröffentlicht in der Reihe Gesundheitsschädliche Arbeitsstoffe , 41. Lieferung, Ausgabe 2006 Der Artikel enthält folgende Kapitel: Toxikokinetik und Metabolismus Erfahrungen beim Menschen Kurzzeitige Exposition Wiederholte Exposition Tierexperimentelle Befunde und In‐vitro‐Untersuchungen Analogie zu Formaldehyd Tumoren Zellproliferation DNA‐Protein‐Crosslinks (DPX) Genotoxizität Bewertung

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Glutaraldehyde (pentanedial) allergic contact dermatitis. Usage test on sole and antecubital fossa: regional variations in response

Maibach¹,

Prystowsky²

1977

Archives of Dermatology

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Glutaraldehyde (pentanedial) is an effective topical therapeutic agent for patients with hyperhidrosis of the soles. A usage test was performed on the soles and antecubital fossae of six previously documented glutaraldehyde-sensitive subjects. All had negative usage test reactions to 25% glutaraldehyde on the soles. But when tested on the antecubital fossae with 2.5% glutaraldehyde, they developed a severe dermatitis within 48 hours. These data demonstrate a striking variation by which glutaraldehyde-sensitive patients tolerate or react to its use in two diverse anatomic sites.

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Eccrine Anhidrosis Due to Glutaraldehyde, Formaldehyde, and Iontophoresis**From the Division of Dermatology, Department of Medicine, University of California School of Medicine, San Francisco, California 94122.

Cited by 38 publications

References 5 publications

The treatment of viral warts with glutaraldehyde

The treatment of viral warts with glutaraldehyde

Glutardialdehyd [MAK Value Documentation in German language, 2006]

Glutaraldehyde (pentanedial) allergic contact dermatitis. Usage test on sole and antecubital fossa: regional variations in response

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