Eccrine Angiomatous Hamartoma

Abstract

A g‐year‐old girl was seen at our outpatient department with a 5‐year history of a slowly enlarging hyperpigmented area with increased sweating on the right upper chest and back. There was no history of pain or tenderness over the lesion. She was the second child of a nonconsanguineous marriage. The older sibling was healthy and there was no family history of similar complaints. Dermatologic examination revealed a large hyperpigmented plaque involving the right upper chest, extending over the right shoulder to the back (Fig. 1). The margins were well defined with raised borders on the upper part; elsewhere it gradually merged with the adjacent normal skin. Two other well‐defined hyper‐pigmented plaques were seen, one 3 × 3 cm over the nape of neck and another 3 × 1 cm over the right supraclavicular fossa. The lesions were nontender and noncompressible. There was increased sweating on the plaque following physical exertion and the plaque could be mapped out with starch and iodine (Fig. 2). Systemic examination of the child was within normal limits. Routine blood and urine examination was normal. Histologic sections showed an increased number of cross‐sections of sweatglands interspersed with dilated vascular spaces, filled with blood, in the mid and lower dermis (Figs. 3 and 4).

Eccrine angiomatous hamartoma: report of seven cases

“…Previous reports have shown EAH to occur most commonly on the lower limbs, 4,10,11 but in all seven of our cases the lesions were on the backs of the hands or fingers; other reported locations however, have included the neck, 12 the face, 2 the thorax 13 and the sacral region. 14 Such lesions generally occur singly, though there have also been reports of multiple lesions, 5,10,12,15 as in our patients 1 and 6.…”

Adult-onset Multiple Eccrine Angiomatous Hamartoma in Enlarging Hairy Plaques

“…We found 12 cases of multiple EAH in the literature (3)(4)(5)(6)(7)(8)(9)(10). No significant dilTcrence in onset age was observed between multiple and single EAH.…”

Late-Onset Eccrine Angiomatous Hamartoma: Clinical, Histological and Imaging Findings

“…In a recent case report reviewing the English literature, 23 other well-documented cases were found, and a few more examples came to record in the French literature [4, 8, 9]. Clinically, the condition presents most often as a solitary papule, nodule or plaque, but multiple variants have been observed [4, 5, 7, 10, 11]. Typically for eccrine disorders, the preferred site of origin of EAH are acral regions, in particular the palms and soles, but the face, neck, abdomen, sacral region and back may also be involved [9, 11, 12, 13].…”

“…Clinically, the condition presents most often as a solitary papule, nodule or plaque, but multiple variants have been observed [4, 5, 7, 10, 11]. Typically for eccrine disorders, the preferred site of origin of EAH are acral regions, in particular the palms and soles, but the face, neck, abdomen, sacral region and back may also be involved [9, 11, 12, 13]. There is no sex predilection, and in general the lesions present at birth or early childhood with a bluish-red coloration [4].…”