Eccrine Angiomatous Hamartoma

Wolf, Ronni; Krakowski, Anatol; Dorfman, Beniamin; Baratz, M

doi:10.1001/archderm.1989.01670230031005

Cited by 31 publications

(9 citation statements)

References 2 publications

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“…The clinical symptoms associated with EAH are pain, tenderness, hyperhidrosis, and localized hypertrichosis 1 . Pain and tenderness in EAH has been attributed to small infiltrating nerves among the eccrine glands, and one report showed that pain was extreme at the beginning and faded with time in about 3 years' duration 1,12 . There is no sex predilection and the lesions usually present at birth or early childhood 1 .…”

Section: Discussionsupporting

confidence: 47%

Multiple mucinous and lipomatous variant of eccrine angiomatous hamartoma associated with spindle cell hemangioma: a novel collision tumor?

Lee¹,

Han²,

Kang³

et al. 2006

J Cutan Pathol

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Eccrine angiomatous hamartoma (EAH) is a rare, benign condition characterized histologically by increased numbers of eccrine elements, as well as numerous capillary channels. In most cases, EAH arises as a single lesion; however, multiple variants have been reported. We report a 35-year-old female patient with multiple, sudoriparous, subcutaneous nodules on the right foot, which showed typical histopathological findings of EAH, and vascular components of the tumor consisted of thin-walled dilated vascular spaces intermixed with spindle cells and some histiocytoid endothelial cells representing spindle cell hemangioma (SCH). To our knowledge, the co-existence of EAH with SCH is a novel finding and not yet described.

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Section: Discussionsupporting

confidence: 47%

Multiple mucinous and lipomatous variant of eccrine angiomatous hamartoma associated with spindle cell hemangioma: a novel collision tumor?

Lee¹,

Han²,

Kang³

et al. 2006

J Cutan Pathol

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“…A MEDLINE search of English‐language articles in the PubMed database using the search terms eccrine angiomatous hamartoma(s), eccrine angiomatous nevus, eccrine hamartoma(s), or mucinous eccrine nevus found 86 articles published between 1968 and 2018 documenting 68 cases of EAH, of which 50 cases were reported to be present at birth. Most reports demonstrated lesion predominance on the distal extremities (See Table ) with fewer accounts detailing distribution on the head, neck, and lower back . Cases reporting lesions in uncommon locations, such as the trunk or abdomen, typically involved only a solitary lesion, whereas EAH occurring as multiple lesions was more often reported in classic sites of involvement such as the arm or leg .…”

Section: Discussionmentioning

confidence: 99%

Congenital eccrine angiomatous hamartoma: Expanding the morphologic presentation and a review of the literature

Smith

DiCaudo

Price

et al. 2019

Pediatric Dermatology

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Eccrine angiomatous hamartoma (EAH) is a rare benign vascular hamartoma characterized histologically by an increased size and number of mature eccrine glands associated with multiple foci of dilated capillaries in the dermis and subcutis. EAH typically presents in children as discrete, solitary nodules, or plaques most commonly located on the extremities. Some cases of EAH have an agminated distribution involving classic locations, or present as solitary lesions in less common locations such as the face, scalp, or trunk. We report the case of congenital EAH in a child with atypical morphological features and pattern of distribution further expanding on the range of presentations classically described.

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“…Other associated adnexal structures have been described supporting its hamartomatous origin 7,8 . Clinically, EAH often resembles a benign nodular hemangioma with a bluish‐red color, however, it has been reported to range from flesh colored to yellow or brown 9 . EAH occurs in both sexes, and in most cases appears at birth or during early childhood.…”

Section: Discussionmentioning

confidence: 99%

“…Gabrielsen et al, 10 in fact, report a case necessitating partial amputation of the finger due to severe pain. Electron microscopy has revealed small infiltrating nerves, 9,11 which is presumed responsible for the associated discomfort.…”

Section: Discussionmentioning

confidence: 99%