Ebola viral disease: a review literature

Moghadam, Saeed Reza Jamali; Omidi, Negar; Bayrami, Samaneh; Moghadam, Sepideh Jamali; SeyedAlinaghi, SeyedAhmad

doi:10.1016/s2221-1691(15)30341-5

Cited by 19 publications

(16 citation statements)

References 33 publications

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“…Edelsburg and Shir-Raz (2015) examined the role of media in the spread of disease in such a crisis situation. Moghadam et al (2015) conducted another review of the different species and structures of the EboV. Liu et al (2015a, b) reviewed the techniques that were used to deal with plague epidemic occurred in Northeast China.…”

Section: Pandemic Ebola Virus Infectionmentioning

confidence: 99%

IoT-based cloud framework to control Ebola virus outbreak

Sareen

Sood

Gupta

2016

J Ambient Intell Human Comput

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Ebola is a deadly infectious virus that spreads very quickly through human-to-human transmission and sometimes death. The continuous detection and remote monitoring of infected patients are required in order to prevent the spread of Ebola virus disease (EVD). Healthcare services based on Internet of Things (IoT) and cloud computing technologies are emerging as a more effective and proactive solution which provides remote continuous monitoring of patients. A novel architecture based on Radio Frequency Identification Device (RFID), wearable sensor technology, and cloud computing infrastructure is proposed for the detection and monitoring of Ebola infected patients. The aim of this work is to prevent the spreading of the infection at the early stage of the outbreak. The J48 decision tree is used to evaluate the level of infection in a user depending on his symptoms. RFID is used to automatically sense the close proximity interactions (CPIs) between users. Temporal Network Analysis (TNA) is applied to describe and monitor the current state of the outbreak using the CPI data. The performance and accuracy of our proposed model are evaluated on Amazon EC2 cloud using synthetic data of two million users. Our proposed model provided 94 % accuracy for the classification and 92 % of the resource utilization.

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Section: Pandemic Ebola Virus Infectionmentioning

confidence: 99%

IoT-based cloud framework to control Ebola virus outbreak

Sareen

Sood

Gupta

2016

J Ambient Intell Human Comput

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“…Since the first reported fatal outbreak in the mid 1970s, members of the Filoviridae virus family, including the Ebola virus (EBOV), the Sudan virus (SUDV), and the Marburg virus (MARV), have continued to devastate many areas across the globe, with mortality rates as high as 90%. 1 , 2 One of the worst outbreaks of EBOV occurred in West Africa from 2013 to 2016, with over 28,000 documented infections and claiming more than 11,000 lives, including nearly 900 health care workers. 1 Filoviruses are a group of enveloped, single-stranded, negative-sense RNA viruses that cause fatigue, vomiting, and severe hemorrhagic fevers.…”

mentioning

confidence: 99%

“… 1 , 3 , 4 Members of the Filoviridae family are zoonotic viruses, where the primary reservoir is speculated to be fruit bats, however, it is unclear if this is the only reservoir or how the transmission to humans occurs. 2 The filoviruses are highly contagious and can easily spread through interaction with an infected individual by direct contact with bodily fluids including vomit, sweat, saliva, and respiratory secretions. 2 , 4 With the high potential for re-emergence of these lethal viruses, particularly due to “super-spreaders”, 5 , 6 it is imperative that a viable treatment option be identified in order to better fight these crippling pathogens before the next outbreak occurs.…”

mentioning

confidence: 99%

Flex-nucleoside analogues – Novel therapeutics against filoviruses

Yates

Raje

Chatterjee

et al. 2017

Bioorganic & Medicinal Chemistry Letters

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Fleximers, a novel type of flexible nucleoside that have garnered attention due to their unprecedented activity against human coronaviruses, have now exhibited highly promising levels of activity against filoviruses. The Flex-nucleoside was the most potent inhibitor against recombinant Ebola virus in Huh7 cells with an EC50 = 2 μM, while the McGuigan prodrug was most active against Sudan virus-infected HeLa cells with an EC50 of 7 μM.

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“…The genus Ebolavirus is one of three members of the Filoviridae family (filovirus), along with the genus Marburgvirus and the genus Cuevavirus. The genus Ebolavirus is made up of five distinct species: Zaire ebolavirus (EBOV), Bundibugyo ebolavirus, Sudan ebolavirus (SUDV), Taï Forest ebolavirus and Reston ebolavirus [26] . Three ebolavirus species have been recorded which cause substantial outbreaks in the African sub-Saharan region: EBOV, SUDV, B. ebolavirus.…”

Section: Introductionmentioning

confidence: 99%