Ebola in Freetown Area, Sierra Leone — A Case Study of 581 Patients

Abstract

CORRESPONDENCEstill presents a huge challenge as we move into the second year of the epidemic in West Africa. WHO Ebola Response TeamA list of authors (members of the WHO Ebola Response Team who contributed to this letter, in alphabetic order) is available with the full text ofthis letter at NEJM.org.

After Ebola in West Africa — Unpredictable Risks, Preventable Epidemics

“…By far the largest numbers of cases and deaths occurred in Guinea, Liberia, and Sierra Leone, but an additional 36 cases were also reported from Italy, Mali, Nigeria, Senegal, Spain, the United Kingdom, and the United States. 1 After reaching a peak of 950 confirmed cases per week in September 2014, the incidence dropped markedly toward the end of that year. But it took much longer to stop all chains of transmission: the outbreaks in Liberia, Sierra Leone, and Guinea ended in May, November, and December 2015, respectively, although additional cases of EVD, probably arising from virus persisting in the tissues and body fluids of survivors, have continued to be reported in all three countries.…”

The Laboratory Diagnosis of Important Zoonotic Infections

“…Olgularda görülen hafif hemorajik semptomlar; peteşi, burun kanaması, ekimoz veya daha ciddi olarak gastrointestinal kanama, şok ya da DIC şeklinde olmaktadır. Genellikle, ağır olgularda, daha sık olarak hemorajik belirtiler görül-mektedir (24,26,27) .…”

“…Çünkü başlangıç bulguları spesifik değildir ve genellikle sıtma, tifo, menejit, sigelloz ve leptospiroz gibi hastalıklarla karışabilir (24,27,28) .…”

Research in Review: Driving Critical Care Practice Change

“…Efficient supportive care with aggressive fluid and electrolyte resuscitation has been shown to decrease EVD mortality from approximately 90% to 31%, but treatments and vaccines are urgently needed. 29 How can these goals be achieved safely and effectively?…”