eATP/P2X7R axis drives nanoparticle induced neutrophil recruitment in the pulmonary microcirculation
Chenxi Li,
Qiongliang Liu,
Lianyong Han
et al.
Abstract:Exposure to nanoparticles (NPs) is frequently associated with adverse cardiovascular effects. In contrast, NPs in nanomedicine hold great promise for precise lung-specific drug delivery, especially considering the extensive pulmonary capillary network that facilitates interactions with bloodstream-suspended particles. Therefore, exact knowledge about interactions and effects of engineered NPs with the pulmonary microcirculation are instrumental for future application of this technology in patients. To unravel … Show more
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