Eating and Weight Changes Following Chemoradiation Therapy for Advanced Head and Neck Cancer

Newman, Lisa A.; Vieira, Francisco; Schwiezer, Valerie; Samant, Sandeep; Murry, Thomas; Woodson, Gayle E.; Kumar, Parvesh; Robbins, K. Thomas

doi:10.1001/archotol.124.5.589

Cited by 145 publications

(148 citation statements)

References 10 publications

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“…Finally, 15 papers answered all four speciWc criteria with (yes) [13,22,23,27,34,40,42,45,51,52,59,60,65,69,81] (Fig. 1).…”

Section: Exclusion Criteriamentioning

confidence: 99%

“…Two studies also included patients with unknown primaries [13,52], one also included paranasal sinuses [27], another included thyroid, paranasal sinus, and external ear cancer [81] and one included a group with diverse disease sites (e.g., parotid, ethmoid cavity, and unknown primary) [13,27,51,52,81]. [23,45,59]. In most of the studies, the inclusion criteria were described in detail.…”

Section: General Wndingsmentioning

confidence: 99%

See 1 more Smart Citation

Functional outcomes and rehabilitation strategies in patients treated with chemoradiotherapy for advanced head and neck cancer: a systematic review

Molen

Rossum

Burkhead

et al. 2008

Eur Arch Otorhinolaryngol

110

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Organ preservation with radiotherapy and concomitant chemotherapy has become an accepted treatment modality in advanced head and neck cancer. Unfortunately, organ preservation is not synonymous with function preservation. The aim of this review was to systematically assess the eVects of the disease and chemoradiotherapy (CRT) on functions such as swallowing, mouth opening, nutrition, pain and quality of life in patients with head and neck cancer. Another aim was to search for (evidence-based) techniques or strategies known to alleviate or rehabilitate the loss of function(s) associated with CRT. Two databases were searched (time period, January 1997 to August 2007) for the terms head and neck cancer, chemotherapy or cisplatin and radiotherapy, and the functional outcomes swallowing, trismus, nutrition, pain and quality of life or a variation of those words. In total, 15 relevant articles were identiWed that met the inclusion criteria. The majority of the studies that met the criteria focused on the outcomes swallowing, quality of life, and nutrition. Two studies reported on the outcome pain, but no paper reported on the outcome trismus. Only two papers mentioned rehabilitation options, but speciWc information was lacking. Further long-term prospective research is essential, not only to determine the function impairment caused by the tumor and CRT, but also to assess the eVects of known and newly developed rehabilitation measures. Therefore, in September 2006, the Netherlands Cancer Institute started a randomised clinical trial (RCT): Prevention of trismus, swallowing and speech problems in patients treated with chemoradiotherapy for advanced head and neck cancer. This systematic review was carried out to collect the baseline information for the future outcomes of this RCT.

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“…Finally, 15 papers answered all four speciWc criteria with (yes) [13,22,23,27,34,40,42,45,51,52,59,60,65,69,81] (Fig. 1).…”

Section: Exclusion Criteriamentioning

confidence: 99%

Section: General Wndingsmentioning

confidence: 99%

Functional outcomes and rehabilitation strategies in patients treated with chemoradiotherapy for advanced head and neck cancer: a systematic review

Molen

Rossum

Burkhead

et al. 2008

Eur Arch Otorhinolaryngol

110

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show abstract

“…While there may be an absence of data specifically relating to the AFRT-CB protocol outcomes at 2 years post-treatment, results from other definitive non-surgical treatment regimens have reported an ongoing functional impact on swallowing and nutrition long-term post-treatment (31)(32)(33)(34)(35). Studies have found that between 5 and 50% of participants are able to tolerate a full diet without restrictions at 1-2 years post-treatment with previously examined radiotherapy protocols for HNC (17, [36][37][38].…”

Section: Discussionmentioning

confidence: 99%

Long-term Functional Outcomes and Patient Perspective Following Altered Fractionation Radiotherapy with Concomitant Boost for Oropharyngeal Cancer

et al. 2012

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“…The functioning between 1 and 6 months may largely be influenced by xerostomia or fibrosis created by radiotherapy [8][9][10][11] , post-surgical scar formation, and atrophic changes of the free flaps, and in this period, patients were trying to control the new oropharyngeal structure. Because these influences may reduce or become stable after 6 months 9 , the swallowing function more than 6 months post-surgically would be unchanged compared to that at 6 months.…”

Section: Discussionmentioning

confidence: 99%

“…Evaluation of the post-surgical swallowing function was performed mainly with videofluoroscopic measures [1][2][3][4][5][6] , but some authors use subjective methods such as questionnaires or similar with or without videofluoroscopic measurements [7][8][9][10][11][12] . Pauloski 4 , Wagner 7 To clarify the course of the recovery of post-surgical swallowing dysfunction between 1 and more than 12 months after surgery, and to determine the correlation among videofluoroscopic measures and medical status indicators, post-surgical oropharyngeal swallow efficiency, nutritional condition, type of nutrition, diet levels, and the occurrence of pneumonia were investigated.…”

Section: Introductionmentioning

confidence: 99%

Recovery from Postsurgical Swallowing Dysfunction in Patients With Oral Cancer

Tei

Maekawa

Kitada

et al. 2007

Journal of Oral and Maxillofacial Surgery

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TEL＆Fax 81-11-706-42831 Purpose: The present study was focused on a comparison of post-surgical oropharyngeal swallow efficiency and medical status indicators. Study design: The swallowing function was assessed in 25 patients (18 males and 7 females) with oral cancer. The swallowing function was assessed preoperatively, and 1, 6, and 12 months and in some cases more than 24 months after surgery. Assessment of the swallowing function consisted of videofluoroscopic evaluation (oropharyngeal swallow efficiency; OPSE) and details of the method of nutrition, diet level, nutritional condition, and occurrence of pneumonia. Results: Post-surgically OPSE did not recover to the preoperative level more than 12 months after surgery. Twenty-one patients (84%) had full oral intake and only three patients (12%) showed poorer nutritional conditions compared to the pre-surgery state. Aspiration pneumonia did not occur more than 12 months after surgery. Conclusions: The patients in the present study showed stable medical status and functional swallowing at the final evaluation despite of the insufficient recovery of the oropharyngeal swallow efficiency revealed by videofluoroscopic evaluation .

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Eating and Weight Changes Following Chemoradiation Therapy for Advanced Head and Neck Cancer

Cited by 145 publications

References 10 publications

Functional outcomes and rehabilitation strategies in patients treated with chemoradiotherapy for advanced head and neck cancer: a systematic review

Functional outcomes and rehabilitation strategies in patients treated with chemoradiotherapy for advanced head and neck cancer: a systematic review

Long-term Functional Outcomes and Patient Perspective Following Altered Fractionation Radiotherapy with Concomitant Boost for Oropharyngeal Cancer

Recovery from Postsurgical Swallowing Dysfunction in Patients With Oral Cancer

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