Easy and low-cost preparation method of magnetic montmorillonite/FexOy composite: initial study for future applications

Tokarčíková, Michaela; Seidlerová, Jana; Motyka, Oldřich; Životský, Ondřej; Drobíková, Klára; Kutláková, Kateřina Mamulová

doi:10.1007/s00706-019-02536-x

Cited by 8 publications

(3 citation statements)

References 28 publications

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“…It has been demonstrated that the composite of MMT and magnetic materials can enhance the saturation magnetization (Ms) and heighten the contrast signal of T2-weighted MRI. [139,140] Therefore, to further optimize the therapeutic effect, CTABmodified MMT has also been used as a magnetic composite loaded with FePt NPs and then FePt@MMT nanocomposites with different magnetic properties are fabricated using one-pot method by regulating the proportion of MMT (Figure 12c). [141] CTAB-modified MMT offers the anchor sites for the nucleation growth of FePt NPs.…”

Section: Multifunctional Applications Of Lcmmentioning

confidence: 99%

Layered Clay Minerals in Cancer Therapy: Recent Progress and Prospects

Xie

Chen

Yang

2023

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Cancer is one of the deadliest diseases, and current treatment regimens suffer from limited efficacy, nonspecific toxicity, and chemoresistance. With the advantages of good biocompatibility, large specific surface area, excellent cation exchange capacity, and easy availability, clay minerals have been receiving ever‐increasing interests in cancer treatment. They can act as carriers to reduce the toxic side effects of chemotherapeutic drugs, and some of their own properties can kill cancer cells, etc. Compared with other morphologies clays, layered clay minerals (LCM) have attracted more and more attention due to adjustable interlayer spacing, easier ion exchange, and stronger adsorption capacity. In this review, the structure, classification, physicochemical properties, and functionalization methods of LCM are summarized. The state‐of‐the‐art progress of LCM in antitumor therapy is systematically described, with emphasis on the application of montmorillonite, kaolinite, and vermiculite. Furthermore, the property–function relationships of LCM are comprehensively illustrated to reveal the design principles of clay‐based antitumor systems. Finally, foreseeable challenges and outlook in this field are discussed.

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Section: Multifunctional Applications Of Lcmmentioning

confidence: 99%

Layered Clay Minerals in Cancer Therapy: Recent Progress and Prospects

Xie

Chen

Yang

2023

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“…Magnetic composites seem to be efficient materials for eliminating pollutants from the aqueous environment due to their high sorption capacity and easy removal by magnetic field post-sorption. Many non-magnetic materials, e.g., clays [ 25 ], chitosan/graphene oxide [ 26 ], carbon-matrix composite [ 27 ], polymer composite [ 28 ], biochar [ 29 ], or peanut husks [ 30 ] can be magnetised. Biochar is a carbon-rich material obtained from the thermochemical conversion of biomass in a closed container with little or no available oxygen [ 31 , 32 ].…”

Section: Introductionmentioning

confidence: 99%

Magnetically Modified Biosorbent for Rapid Beryllium Elimination from the Aqueous Environment

et al. 2021

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Although both beryllium and its compounds display high toxicity, little attention has been focused on the removal of beryllium from wastewaters. In this research, magnetically modified biochar obtained from poor-quality wheat with two distinct FexOy contents was studied as a sorbent for the elimination of beryllium from an aqueous solution. The determined elimination efficiency was higher than 80% in both prepared composites, and the presence of FexOy did not affect the sorption properties. The experimental qmax values were determined to be 1.44 mg/g for original biochar and biochar with lower content of iron and 1.45 mg/g for the biochar with higher iron content. The optimum pH values favorable for sorption were determined to be 6. After the sorption procedure, the sorbent was still magnetically active enough to be removed from the solution by a magnet. Using magnetically modified sorbents proved to be an easy to apply, low-cost, and effective technique.

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“…The use of MMT combined with magnetic materials has been proven to increase the saturation magnetization (Ms) and enhance the contrast signal of T2-weighted MRI. [30][31][32] FePt NPs included in MMT-modi ed cetyltrimethylammonium bromide (CTAB) have been synthesized through a simple process using the onepot method. Triethylene glycol (TEG) functions as both a solvent and reductant, whereas MMT-modi ed CTAB provides anchoring sites for the nucleation growth of FePt NPs.…”

Section: Introductionmentioning

confidence: 99%

Magnetically Guided Theranostics: Enhancing the Contrast of Magnetic Resonance Imaging With Multiple-Layer Montmorillonite-Based Iron/Platinum Nanoparticles for the Treatment of Orthotopic Hepatocellular Carcinoma

Chan

Chung

et al. 2021

Preprint

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In Asia, including Taiwan, malignant tumors such as Hepatocellular carcinoma (HCC) one of the liver cancer is the most diagnosed subtype. Magnetic resonance imaging (MRI) has been a typical diagnostic method for accurately diagnosing HCC. When it is difficult to demonstrate non-enhanced MRI of tumors, radiologists can use contrast agents (such as Gd3+, Fe3O4, or FePt) for T1-weighted and T2-weighted imaging, which can remain in the liver for a long time to facilitate diagnosis via MRI. However, sometimes it is difficult for T2-weighted imaging to detect small tumor lesions because the liver tissue may actively absorb iron ions. This makes early cancer detection a challenging goal. To develop a method that can more efficiently diagnose and simultaneously treat HCC during MRI examination, we designed a functionalized montmorillonite (MMT) material with a porous structure to benefit related drugs, such as mitoxantrone (MIT) delivery or as a carrier for the FePt nanoparticles (FePt NPs) to introduce cancer therapy. Multifunctional FePt@MMT can simultaneously visualize and treat various diseases and can be used as an inducer of magnetic fluid hyperthermia (MFH). After loading the drug MIT, FePt@MMT-MIT provides both MFH treatment and chemotherapy in one nanosystem. These results ultimately prove that functionalized FePt@MMT-MIT could be integrated as a versatile drugs delivery system by combining with MRI, chemotherapeutic drugs, and magnetic guide targeting.

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Easy and low-cost preparation method of magnetic montmorillonite/FexOy composite: initial study for future applications

Cited by 8 publications

References 28 publications

Layered Clay Minerals in Cancer Therapy: Recent Progress and Prospects

Layered Clay Minerals in Cancer Therapy: Recent Progress and Prospects

Magnetically Modified Biosorbent for Rapid Beryllium Elimination from the Aqueous Environment

Magnetically Guided Theranostics: Enhancing the Contrast of Magnetic Resonance Imaging With Multiple-Layer Montmorillonite-Based Iron/Platinum Nanoparticles for the Treatment of Orthotopic Hepatocellular Carcinoma

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