Easy Access to Aryl‐ and Heteroaryl‐Annulated[a]carbazoles by the Indium‐Catalyzed Reaction of 2‐Arylindoles with Propargyl Ethers

In(OTf)3‐Catalyzed Tandem Nucleophilic Addition and Cyclization of ortho‐Alkynylarylaldimines to 1,2‐Dihydroisoquinolines

“…Recently, certain indium( III ) salts, as well as other transition‐metal compounds, were found to have π acidity and to activate CC multiple bonds by coordination to π electrons 3. Several InX 3 ‐catalyzed nucleophilic additions of arenes,4a,b 1,3‐dicarbonyl compounds,4c,d and heteroatomic compounds, such as anilines4e,f and thiols4g to triple bonds, have been reported 4…”

Gold‐Catalyzed Cyclization of 1‐(Indol‐3‐yl)‐3‐alkyn‐1‐ols: Facile Synthesis of Diversified Carbazoles

“…Although a lot of synthetic methodologies to construct carbozales have been reported, [7] an efficient and mild preparative route to specific substituted carbozales is still highly desirable. [8] Gold-catalyzed cyclization reactions are a powerful tool for the synthesis of indole-containing structures, including carbazoles. [9] For example, gold-catalyzed deacylative cycloisomerization of 3-acylindole/ynes (reported by Liu et al) and intramolecular hydroarylation of 1-(indol-2-yl)-2,3-allenols or 1-(indol-2-yl)-3-alkyn-1-ols (reported by the groups of Ma, Alcaide) are efficient synthetic routes to carbazoles.…”

Synthetic Utility of 2-Furylmethylene-2,3,4,9-Tetrahydrocarbazol-1-Ones: Syntheses of Pyrazolo, Isoxazolo, Pyrido and Pyrimido Annelated Carbazoles

“…Calcd for C 17 H 12 N 2 O 2 : C,73.90;H,4.38;N,10.14. Found: C,73.75;H,4.22;N,10.07%. (17), 169 (14), 115 (16), 91 (19), 67 (12).…”

“…The rapidly growing class of heteroaryl-condensed carbazoles has begun to attract increasing interest because of their broad spectrum of useful biological activities. [4][5][6][7][8][9] Most heteroaryl carbazoles reported [10][11][12] contain a heteroaryl moiety fused with a carbazole; however, there are few reports where the heteroaryl moiety is substituted with a carbazole unit.…”