East-West Differences in Clinical Manifestations of COVID-19 Patients: A Systematic Literature Review and Meta-Analysis

Liu, Xiucheng; Li, Xiang; Sun, Tao; Zhou, Yeqing; Zou, Chenghang; Zhang, Hao

doi:10.2139/ssrn.3627336

Cited by 3 publications

(7 citation statements)

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“…Most meta-analysis showed that the prevalence of liver injury was about 16%–29% [ 7 , 9 , 10 , 38 , 45 , 53 , 63 , 65 , 66 , 67 , 68 ]. Additionally, the prevalence of liver injury during hospitalization was higher than that at admission [ 30 , 69 ].…”

Section: Covid-19 and The Livermentioning

confidence: 99%

“…The levels of AST, ALT, TBIL, globulin, GGT, ALP, and PT increased, while levels of ALB decreased among COVID-19 patients with liver injury during COVID-19 progression. The proportion of increased AST was 15%–34% [ 7 , 29 , 30 , 35 , 37 , 63 , 67 , 70 , 71 , 72 , 73 , 74 , 75 ]. Labenz et al [72] reported that the mean AST value was 33 U/L among COVID-19 patients, and Bansal et al [76] reported that the mean AST value was 27.28 IU/L among COVID-19 patients.…”

Section: Covid-19 and The Livermentioning

confidence: 99%

“…Labenz et al [72] reported that the mean AST value was 33 U/L among COVID-19 patients, and Bansal et al [76] reported that the mean AST value was 27.28 IU/L among COVID-19 patients. The proportion of increased ALT was 15%–28% [ 7 , 29 , 30 , 35 , 37 , 63 , 67 , 70 , 71 , 72 , 73 , 74 , 75 ].…”

Section: Covid-19 and The Livermentioning

confidence: 99%

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COVID-19 and liver dysfunction: Epidemiology, association and potential mechanisms

Song

Liu

et al. 2022

Clinics and Research in Hepatology and Gastroenterology

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Section: Covid-19 and The Livermentioning

confidence: 99%

Section: Covid-19 and The Livermentioning

confidence: 99%

See 1 more Smart Citation

COVID-19 and liver dysfunction: Epidemiology, association and potential mechanisms

Song

Liu

et al. 2022

Clinics and Research in Hepatology and Gastroenterology

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“…Eye symptoms (7,8) were among the most discussed statements, and the corresponding statements had relatively low levels of approval (Figure 1). Nasal pain ( 5) was regarded as impractical by six participants, which was also reflected by a relatively low level of 3).…”

Section: Covid−19mentioning

confidence: 99%

“…4 Impaired sense of smell and taste has emerged as an alarming symptom of SARS-CoV-2 infection in the West, but not so much in Asia. [5][6][7][8][9] Presentation in the upper respiratory tract has also been described as extremely variable across age groups, 10 making it difficult to distinguish COVID-19 from common upper respiratory infections (e.g. croup in children 10 ).…”

Section: Introductionmentioning

confidence: 99%

Differentiation of COVID‐19 signs and symptoms from allergic rhinitis and common cold: An ARIA‐EAACI‐GA²LEN consensus

Hagemann

Onorato²,

Jutel

et al. 2021

Allergy

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Background: Although there are many asymptomatic patients, one of the problems of COVID-19 is early recognition of the disease. COVID-19 symptoms are polymorphic and may include upper respiratory symptoms. However, COVID-19 symptoms may be mistaken with the common cold or allergic rhinitis. An ARIA-EAACI study group attempted to differentiate upper respiratory symptoms between the three diseases.Methods: A modified Delphi process was used. The ARIA members who were seeing COVID-19 patients were asked to fill in a questionnaire on the upper airway symptoms of COVID-19, common cold and allergic rhinitis.Results: Among the 192 ARIA members who were invited to respond to the questionnaire, 89 responded and 87 questionnaires were analysed. The consensus was then reported. A two-way ANOVA revealed significant differences in the symptom intensity between the three diseases (p < .001). Conclusions:This modified Delphi approach enabled the differentiation of upper respiratory symptoms between COVID-19, the common cold and allergic rhinitis. An electronic algorithm will be devised using the questionnaire.

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Prognostic factors for mortality, ICU and hospital admission due to SARS-CoV-2: A systematic review and meta-analysis of cohort studies in Europe

Vardavas

Mathioudakis

Nikitara

et al. 2022

Preprint

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Background: As mortality from COVID-19 is strongly age-dependent, we aimed to identify population subgroups at an elevated risk for adverse outcomes from COVID-19 using age/gender-adjusted data from European cohort studies with the aim to identify populations that could potentially benefit from booster vaccinations. Methods: We performed a systematic literature review and meta-analysis to investigate the role of underlying medical conditions as prognostic factors for adverse outcomes due to SARS-CoV-2, including death, hospitalisation, Intensive Care Unit (ICU) admission, and mechanical ventilation within three separate settings (community, hospital and ICU). Cohort studies that reported at least age and gender-adjusted data from Europe were identified through a search of peer-reviewed articles published until 11th June 2021 in Ovid Medline and Embase. Results are presented as Odds Ratios (ORs) with 95% confidence intervals (95%C.I.) and absolute risk differences (RD) in deaths per 1,000 COVID-19 patients. Findings: We included 88 cohort studies with age/gender adjusted data from 6,653,207 SARS-CoV-2 patients from Europe. Hospital-based mortality was associated with high and moderate certainty evidence for solid organ tumours, diabetes mellitus, renal disease, arrhythmia, ischemic heart disease, liver disease, and obesity, while a higher risk, albeit with low certainty, was noted for chronic obstructive pulmonary disease and heart failure. Community-based mortality was associated with a history of heart failure, stroke, diabetes, and end-stage renal disease. Evidence of high/moderate certainty revealed a strong association between hospitalisation for COVID-19 and solid organ transplant recipients, sleep apnoea, diabetes, stroke, and liver disease. Interpretation: The results confirmed the strong association between specific prognostic factors and mortality and hospital admission. Prioritisation of booster vaccinations and the implementation of non-pharmaceutical protective measures for these populations may contribute to a reduction in COVID-19 mortality, ICU and hospital admissions. Funding: European Centre for Disease Prevention and Control (ECDC) under specific contract No. 10 ECD.11843 within Framework contract ECDC/2019/001 Lot 1B.

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East-West Differences in Clinical Manifestations of COVID-19 Patients: A Systematic Literature Review and Meta-Analysis

Cited by 3 publications

References 0 publications

COVID-19 and liver dysfunction: Epidemiology, association and potential mechanisms

COVID-19 and liver dysfunction: Epidemiology, association and potential mechanisms

Differentiation of COVID‐19 signs and symptoms from allergic rhinitis and common cold: An ARIA‐EAACI‐GA²LEN consensus

Prognostic factors for mortality, ICU and hospital admission due to SARS-CoV-2: A systematic review and meta-analysis of cohort studies in Europe

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East-West Differences in Clinical Manifestations of COVID-19 Patients: A Systematic Literature Review and Meta-Analysis

Cited by 3 publications

References 0 publications

COVID-19 and liver dysfunction: Epidemiology, association and potential mechanisms

COVID-19 and liver dysfunction: Epidemiology, association and potential mechanisms

Differentiation of COVID‐19 signs and symptoms from allergic rhinitis and common cold: An ARIA‐EAACI‐GA2LEN consensus

Prognostic factors for mortality, ICU and hospital admission due to SARS-CoV-2: A systematic review and meta-analysis of cohort studies in Europe

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Differentiation of COVID‐19 signs and symptoms from allergic rhinitis and common cold: An ARIA‐EAACI‐GA²LEN consensus