Earth-Abundant d-Block Metal Nanocatalysis for Coupling Reactions in Polyols

Abstract

Green Chemistry concepts have directed chemists to conceive and develop AQ1 sustainable procedures, from the starting materials choice through reaction and analysis conditions, including suitable engineering aspects, to the impact of products, comprising recycling, and waste management. Industrial processes in Fine and Pharmaceutical Chemistry sector have high E factors compared to oil and bulk chemicals industry. Thus, the development of catalytic methods leading to high added value products is crucial, as well as waste minimization through selective transformations. Catalysts from 3d metals, compared to "heavy" metals, are greener, although a combination of different approaches is needed for efficient and viable processes. In contrast to 4d and 5d metals, catalysis with earth-abundant metals is less developed, even less concerning nanocatalysts. Metal nanoparticles, due to their unique electronic and structural properties, induce original reactivities allowing a plethora of transformations. Besides, solvents, present in most steps, represent a major economic and environmental concern. In addition, they can have a dramatic influence on the stabilization of MNP and hence, a huge impact on catalytic activity and recycling. This chapter gives a perspective on 3d metal-based nanocatalysts in polyols applied in couplings, reactions present in many methodologies to produce fine chemicals in a sustainable fashion. Keywords 3d metals • Metal nanoparticles • Catalysis • Couplings • Polyols Dedicated to Prof. Guillermo Muller for his thorough contributions in Organometallic Chemistry and Homogeneous Catalysis.