Early Versus Late Initiation of Renal Replacement Therapy in Critically Ill Patients With Acute Kidney Injury After Cardiac Surgery: A Systematic Review and Meta-analysis

Acute Kidney Injury and Long-term Risk of Cardiovascular Events After Cardiac Surgery: A Population-Based Cohort Study

“…However, research shows that early initiation compared to late initiation of renal replacement therapy in severe AKI after cardiac surgery diminished short-term mortality, odds ratio 0.29 (95% CI: 0.16-0.52). 32 This warrants further investigation with regard to cardiovascular events.…”

The effect of early versus late initiation of renal replacement therapy in patients with acute kidney injury: A meta-analysis with trial sequential analysis of randomized controlled trials

“…Liu [33] included 9 retrospective cohort studies and 2 RCTs (841 patients). This meta-analysis showed that early initiation of RRT in patients with AKI after cardiac surgery resulted in lower mortality at 28 days (OR = 0.29, 95% CI, 0.16–0.52, P <0.0001, I 2 = 56%) and shorter ICU LOS (3.9 [1.5–6.3] days, P <0.0001, I 2 = 99%).…”

“…This meta-analysis showed that early initiation of RRT in patients with AKI after cardiac surgery resulted in lower mortality at 28 days (OR = 0.29, 95% CI, 0.16–0.52, P <0.0001, I 2 = 56%) and shorter ICU LOS (3.9 [1.5–6.3] days, P <0.0001, I 2 = 99%). Although the majority of these clinical data appear to support the view that early RRT reduces mortality in patients with AKI, these observational data may suffer from a number of potential methodological limitations, leading to biased results [33]. …”

The assessment of lesions of the Achilles tendon by ultrasound imaging in inflammatory arthritis: A systematic review and meta-analysis

“…The total percentage score for each paper was determined. In the absence of validated cut-off scores and following a review of past articles that have applied the Downs and Black criteria, studies that scored: Z11 (85%) were deemed high quality; 8-11 (61-84%) moderate quality; and o8 (61%) poor quality [15,16].…”

“…The search was conducted between June and July 2014, and the search strategy combined terms appropriate to IA: RA, SpA, ankylosing spondylitis (AS), psoriatic arthritis (PsA), gout and calcium pyrophosphate deposition (CPPD) and AT pathology and US imaging ( Table 1). The term SpA encompasses a heterogeneous group of conditions, characterised by vertebral involvement, peripheral oligoarthritis or polyarthritis, enthesitis, AS, PsA and undifferentiated spondyloenthesoarthritis [14,15]. The review included SpA but also reported on AS and PsA as separate diseases.…”