Early versus delayed laparoscopic cholecystectomy for acute cholecystitis: a prospective randomized trial

Kolla, Surendra B.; Aggarwal, Sandeep; Kumar, Abhinav; Kumar, Ramesh; Chumber, Sunil; Parshad, Rajinder; Seenu, Vuthaluru

doi:10.1007/s00464-003-9230-6

Cited by 247 publications

(277 citation statements)

References 14 publications

Supporting

Mentioning

238

Contrasting

Unclassified

Order By: Relevance

“…6 Timing of LC for AC has been controversially discussed. [22][23] In the past, many authors argued that early LC for AC is associated with a high risk of complications. In 1992, Frazee et al 17 declared AC as a contraindication for LC.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Is the Male Gender an Independent Risk Factor for Complication in Patients Undergoing Laparoscopic Cholecystectomy for Acute Cholecystitis?

Ambe

Köhler²

2015

International Surgery

View full text Add to dashboard Cite

This paper was designed to investigate the gender dependent risk of complication in patients undergoing laparoscopic cholecystectomy for acute cholecystitis. Laparoscopic cholecystectomy is the standard procedure for benign gallbladder disorders. The role of gender as an independent risk factor for complicated laparoscopic cholecystectomy remains unclear. A retrospective single-center analysis of laparoscopic cholecystectomies performed for acute cholecystitis over a 5-year period in a community hospital was performed. Within the period of examination, 1884 laparoscopic cholecystectomies were performed. The diagnosis was acute cholecystitis in 779 cases (462 female, 317 male). The male group was significantly older (P ¼ 0.001). Surgery lasted significantly longer in the male group (P ¼ 0.008). Conversion was done in 35 cases (4.5%). There was no significant difference in the rate of conversion between both groups. However the rate of conversion was significantly higher in male patients . 65 years (P ¼ 0.006). The length of postoperative hospital stay was significantly longer in the male group (P ¼ 0.007), in the group . 65 years (P ¼ 0.001) and following conversion to open surgery (P ¼ 0.001). The male gender was identified as an independent risk factor for prolonged laparoscopic cholecystectomy on multivariate analysis. The male gender could be an independent risk factor for complicated or challenging surgery in patients undergoing laparoscopic cholecystectomy for acute cholecystitis.

show abstract

Section: Discussionmentioning

confidence: 99%

“…The median duration of surgery for this study was 37 minutes (11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22) minutes. The corresponding values were 36 minutes (11-221) minutes and 39 minutes (12-159) minutes for the female and male group, respectively.…”

Section: Duration Of Surgerymentioning

confidence: 99%

Is the Male Gender an Independent Risk Factor for Complication in Patients Undergoing Laparoscopic Cholecystectomy for Acute Cholecystitis?

Ambe

Köhler²

2015

International Surgery

View full text Add to dashboard Cite

show abstract

“…1 However, in the early days, acute cholecystitis was a contraindication of laparoscopic cholecystectomy, and patients with acute cholecystitis were managed conservatively and discharged for re-admission in order to have elective surgery performed for the definitive treatment. 2,3 Then, randomized controlled trials and meta-analyses had shown the benefits of early surgery (within the acute admission period, which is 24 to 72 hours) compared with delayed cholecystectomy with respect to hospital stay and costs, with no significant difference in morbidity and mortality.…”

mentioning

confidence: 99%

Early Versus Delayed Laparoscopic Cholecystectomy for Acute Cholecystitis: A Prospective, Randomized Study

Özkardeş¹,

Tokaç²,

Dumlu³

et al. 2014

International Surgery

View full text Add to dashboard Cite

We aimed to compare the clinical outcome and cost of early versus delayed laparoscopic cholecystectomy for acute cholecystitis. Sixty patients with acute cholecystitis were randomized into early (within 24 hours of admission) or delayed (after 6-8 weeks of conservative treatment) laparoscopic cholecystectomy groups. There was no significant difference between study groups in terms of operation time and rates for conversion to open cholecystectomy. On the other hand, total hospital stay was longer (5.2 6 1.40 versus 7.8 6 1.65 days; P ¼ 0.04) and total costs were higher (2500.97 6 755.265 versus 3713.47 6 517.331 Turkish Lira; P ¼ 0.03) in the delayed laparoscopic cholecystectomy group. Intraoperative and postoperative complications were recorded in 8 patients in the early laparoscopic cholecystectomy group, whereas no complications occurred in the delayed laparoscopic cholecystectomy group (P ¼ 0.002). Despite intraoperative and postoperative complications being associated more with early laparoscopic cholecystectomy compared with delayed intervention, early laparoscopic cholecystectomy should be preferred for treatment of acute cholecystitis because of its advantages of shorter hospital stay and lower cost.

show abstract

“…Although an open approach remains a valid option in complicated cases (e.g., gangrenous cholecystitis, etc. ), LC is reportedly safe and beneficial according to most series [4][5][6][7][8]. As the latter are issued from experts, they may not reflect general surgical practice, in particular regarding overall mortality and biliary complication rate.…”

mentioning

confidence: 99%

Surgical management of acute cholecystitis: results of a 2-year prospective multicenter survey in Belgium

Navez

Ungureanu²,

Michiels³

et al. 2012

Surg Endosc

View full text Add to dashboard Cite

Background Laparoscopic cholecystectomy is considered nowadays as the standard management of acute cholecystitis (AC). However, results from multicentric studies in the general surgical community are still lacking. Methods A prospective multicenter survey of surgical management of AC patients was conducted over a 2-year period in Belgium. Operative features and patients' clinical outcome were recorded. The impact of independent predictive factors on the choice of surgical approach, the risk of conversion, and the occurrence of postoperative complications was studied by multivariate logistic regression analysis.

show abstract

Early versus delayed laparoscopic cholecystectomy for acute cholecystitis: a prospective randomized trial

Abstract: Early laparoscopic cholecystectomy for acute cholecystitis is safe and feasible, offering the additional benefit of a shorter hospital stay. It should be offered to patients with acute cholecystitis, provided the surgery is performed within 72 to 96 h of the onset of symptoms.

Cited by 247 publications

References 14 publications

Is the Male Gender an Independent Risk Factor for Complication in Patients Undergoing Laparoscopic Cholecystectomy for Acute Cholecystitis?

Is the Male Gender an Independent Risk Factor for Complication in Patients Undergoing Laparoscopic Cholecystectomy for Acute Cholecystitis?

Early Versus Delayed Laparoscopic Cholecystectomy for Acute Cholecystitis: A Prospective, Randomized Study

Surgical management of acute cholecystitis: results of a 2-year prospective multicenter survey in Belgium

Contact Info

Product

Resources

About