Early Thoracic Sympathetic Block Improves the Treatment Effect for Upper Extremity Neuropathic Pain

Yoo, Hyung Seok; Nahm, Francis Sahngun; Lee, Pyung Bok; Lee, Chul Joong

doi:10.1213/ane.0b013e3182274803

Cited by 25 publications

(19 citation statements)

References 33 publications

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“…Several studies proved this hypothesis and showed dramatic improvement in pain relief after sympathetic blockage [37], sympathectomy [38], or temporary blockage with α -adrenergic antagonists with intravenous phentolamine [39]. …”

Section: Neuropathic Pain Generation Pathogenesismentioning

confidence: 99%

Pathogenesis of Painful Diabetic Neuropathy

Aslam

Singh

Rajbhandari

2014

Pain Research and Treatment

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The prevalence of diabetes is rising globally and, as a result, its associated complications are also rising. Painful diabetic neuropathy (PDN) is a well-known complication of diabetes and the most common cause of all neuropathic pain. About one-third of all diabetes patients suffer from PDN. It has a huge effect on a person's daily life, both physically and mentally. Despite huge advances in diabetes and neurology, the exact mechanism of pain causation in PDN is still not clear. The origin of pain could be in the peripheral nerves of the central nervous system. In this review, we discuss various possible mechanisms of the pathogenesis of pain in PDN. We discuss the role of hyperglycaemia in altering the physiology of peripheral nerves. We also describe central mechanisms of pain.

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Section: Neuropathic Pain Generation Pathogenesismentioning

confidence: 99%

Pathogenesis of Painful Diabetic Neuropathy

Aslam

Singh

Rajbhandari

2014

Pain Research and Treatment

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“…The symptoms of neuropathic pain are: allodynia (pain perception upon the innocuous tactile stimuli), hyperalgesia (exaggerated pain sensations by mildly noxious stimuli) and spontaneous pain with varying intensity. It is an obstacle in daily activities and can decrease quality of life considerably (Pickering et al, 2011;Treede et al, 2008;Xie et al, 2008;Yoo et al, 2011). The pathophysiology of neuropathic pain is complex.…”

Section: Introductionmentioning

confidence: 99%

The influence of spatial pulsed magnetic field application on neuropathic pain after tibial nerve transection in rat

Szajkowski¹,

Marcol²,

Właszczuk³

et al. 2013

Electromagnetic Biology and Medicine

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The purpose of the study was to examine the influence of the spatial variable magnetic field (induction: 150-300 µT, 80-150 µT, 20-80 µT; frequency 40 Hz) on neuropathic pain after tibial nerve transection. The experiments were carried out on 64 male Wistar C rats. The exposure of animals to magnetic field was performed 1 d/20 min., 5 d/week, for 28 d. Behavioural tests assessing the intensity of allodynia and sensitivity to mechanical and thermal stimuli were conducted 1 d prior to surgery and 3, 7, 14, 21 and 28 d after the surgery. The extent of autotomy was examined. Histological and immunohistochemical analysis was performed. The use of extremely low-frequency magnetic fields of minimal induction values (20-80 µT/40 Hz) decreased pain in rats after nerve transection. The nociceptive sensitivity of healthy rats was not changed following the exposition to the spatial magnetic field of the low frequency. The results of histological and immunohistochemical investigations confirm those findings. Our results indicate that extremely low-frequency magnetic field may be useful in the neuropathic pain therapy.

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“…In the preclinical and clinical studies, it was shown that early application of nerve block can prevent or reduce neuropathic pain. [10,11] Therefore, we decided to turn our therapeutic focus toward nerve block.…”

Section: Discussionmentioning

confidence: 99%

Treatment of great auricular neuralgia with real-time ultrasound-guided great auricular nerve block

Jeon

Kim²

2017

Medicine

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Rationale:The great auricular nerve can be damaged by the neck surgery, tumor, and long-time pressure on the neck. But, great auricular neuralgia is very rare condition. It was managed by several medication and landmark-based great auricular nerve block with poor prognosis.Patient concerns:A 25-year-old man presented with a pain in the left lateral neck and auricle.Diagnosis:He was diagnosed with great auricular neuralgia.Interventions:His pain was not reduced by medication. Therefore, the great auricular nerve block with local anesthetics and steroid was performed under ultrasound guidance.Outcomes:Ultrasound guided great auricular nerve block alleviated great auricular neuralgia.Lessons:This medication-resistant great auricular neuralgia was treated by the ultrasound guided great auricular nerve block with local anesthetic agent and steroid. Therefore, great auricular nerve block can be a good treatment option of medication resistant great auricular neuralgia.

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Early Thoracic Sympathetic Block Improves the Treatment Effect for Upper Extremity Neuropathic Pain

Abstract: The results showed that an earlier TSB produced a better outcome for patients with chronic pain syndrome. Thus, early TSB should be performed in patients with chronic pain in the upper extremities.

Cited by 25 publications

References 33 publications

Pathogenesis of Painful Diabetic Neuropathy

Pathogenesis of Painful Diabetic Neuropathy

The influence of spatial pulsed magnetic field application on neuropathic pain after tibial nerve transection in rat

Treatment of great auricular neuralgia with real-time ultrasound-guided great auricular nerve block

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