Early Syringomyelia in Tubercular Meningitis: A Rare Occurrence

Pandey, .

doi:10.4021/jnr172w

Cited by 4 publications

(7 citation statements)

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“…In our case, the patient developed syringomyelia seventeen days after the initial diagnosis of TBM, suggesting an acute course, which is exceptionally rare as there have only been few reports identifying syringomyelia as an early complication of TBM [8][9][10][11]. The features of these previous cases are summarized in Table 1.…”

Section: Discussionmentioning

confidence: 67%

Acute development of syringomyelia following TBM in a pediatric case

et al. 2021

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Background Syringomyelia secondary to tuberculous meningitis (TBM) is rarely reported, and is usually a late complication. Acute development of syringomyelia following TBM is an exceedingly rare condition with only a few cases published in adults and no previous reports in children. Case presentation We present a case of syringomyelia as an acute complication of TBM in a 12-year-old boy despite appropriate chemotherapy. The patient developed spastic paraplegia of the lower limbs with fecal and urinary retention seventeen days after the initial symptoms of TBM. He was managed successfully with continued chemotherapy and high-dose intravenous immunoglobulin (IVIG). Conclusions This case reminds us that syrinx formation may be responsible for early neurological deterioration in children being managed for TBM. IVIG may be considered as an effective treatment option for this situation.

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Section: Discussionmentioning

confidence: 67%

Acute development of syringomyelia following TBM in a pediatric case

et al. 2021

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“…Focal scarring causes a block in the circulation of CSF, which also play vital role in formation of syrinx 1,2 .…”

Section: Syringo-peritoneal Shunt For Late Syringomyelia In a Patient...mentioning

confidence: 99%

“…This patient received full course of antitubercular treatment and despite that she started to deteriorate to form a syrinx after a period. The latent period between the initial inflammatory events and late development of symptoms related to syringomyelia is usually long and varies between 7-28 years 1,2,15,17 . Formation of syrinx in acute stages and in a relatively short period of time have also been reported on several occasions 2,12,15,16 .…”

Section: Syringo-peritoneal Shunt For Late Syringomyelia In a Patient...mentioning

confidence: 99%

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Syringo-Peritoneal Shunt for Late Syringomyelia In a Patient of Post Tubercular Meningitis: A Case Report With Literature Review

Chowdhury

Rahman

Karim

et al. 2018

J Chittagong Med Coll Teachers Ass

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Background: Tuberculosis (TB) is one of the commonest infectious diseases in the developing countries like Bangladesh. Tubercular Meningitis (TBM) is a common sequel of TB involving the Central Nervous System (CNS) and is one of the leading causes of mortality and morbidity. Syringomyelia following TBM as late or early complication of TB is very rare. Case Description: We report a case of syrigomyelia in a 32 years old lady as a sequel, following treatment for tubercular meningitis after 8 years of successful treatment of tubercular meningitis with a full course of Anti tubercular drugs. She developed gradual weakness of her both lower limbs along with tingling and numbness and bladder incontinence for 5 months before presentation. MRI of Brain and Spine revealed syringomyelia from upper cervical region down to lower dorsal region. Syringostomy at D7 level was done initially but with not much significant improvement. Rather over a period of time she deteriorated and became bed ridden. We put a syringoperitoneal shunt. One month after surgery her lower limb power improved to MRC Grade 4 which enabled her to walk with support. She also had significant improvement of bladder function with full control. Conclusion: High index of suspicion with new neurological signs in patients of TBM, despite proper treatment, is worthwhile considering syringomyelia as a possible cause. Timely diagnosis and appropriate treatment thereby can reduce the morbidity with better neurological outcome. JCMCTA 2017 ; 28 (2) : 116-121

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“…The probable mechanisms of syrinx development in TBM are tubercular vasculitis, producing cord ischemia and softening; spinal subarachnoid space scarring, causing reduced compliance of the subarachnoid space; and the patent Virchow-Robin spaces in the spinal cord, providing a channel for the CSF to enter into the central canal and communicating hydrocephalus with acute rise in intracranial pressure. [25] The other spinal complications of TBM are arachnoiditis, vasculitic infarcts, and tuberculomas.…”

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confidence: 99%