Early sepsis, obstructive jaundice and right‐sided diaphragmatic hernia in the newborn

Abstract

A male newborn was admitted to our Unit because of early sepsis and shock. He required antimicrobial therapy and mechanical ventilation and initially did well, although he exhibited jaundice and cholestasis. During the second week he deteriorated, with radiological opacification of the right hemithorax and pleural effusion, and did poorly in spite of antibiotical therapy and drainage of the effusion. In the third week, the X‐ray suggested some bowel loops in the right hemithorax. A right‐sided diaphragmatic hernia was confirmed by a CT‐scan, and surgery was performed with good outcome. The association of delayed‐onset right‐sided CDH following early sepsis and obstructive jaundice has not been published before, and illustrates a scarcely known form of presentation of this condition.

Right congenital diaphragmatic hernia: an 18-year experience

“…In our experience, 8 (27.6%) of 29 cases presented beyond 7 days of life, but in just 1 case the peritoneal sac was found. Late-presenting RCDH is characterized by a variety of clinical pictures [14,18,19]. In our series, 2 infants, as well described in the literature [20], presented in the first days of life with signs and symptoms of group B b-hemolytic Streptococcus infection.…”

Effect of new onset of jaundice on outcomes in patients with sepsis: A population-based propensity score-matched study

“…Several small scale studies explore the relationship between jaundice and bacteria infection (7), or infant jaundice and sepsis (8), however, yet there are no data from large scale studies investigating the characteristic and influence of jaundice in adults with sepsis. And no study focuses on new onset of jaundice in sepsis before.…”