Early response of the gut microbiome and serum metabolites to Cheonggukjang intake in healthy Korean subjects

Factors driving the inter-individual variability in the metabolism and bioavailability of (poly)phenolic metabolites: A systematic review of human studies

“…Interestingly, unchanged isoflavone metabolites (in particular daidzein, genistein, and glycitein) are excreted in higher amounts in equol non-producers [ 119 , 134 ]. A recent work reported that the AUC 0-24h and C max values of 5-hydroxyequol, but not of other isoflavone metabolites changed according to the enterotype, with subjects belonging to Prevotella -rich enterotype presenting higher values than in the Bacteroides and Ruminococcaceae enterotypes [ 142 ].…”