Early recanalization and plasma brain natriuretic peptide as an indicator of left ventricular function after acute myocardial infarction

Inoue, Teruo; Sakuma, Masashi; Yaguchi, Isao; Mizoguchi, Keiichi; Uchida, Toshihiko; Takayanagi, Kunio; Hayashi, Terumi; Morooka, Shigenori

doi:10.1067/mhj.2002.122170

Cited by 22 publications

(10 citation statements)

References 25 publications

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“…4,13) In a study by Inoue, et al, the highest levels of BNP were reached 24 hours after onset of AMI, which was the most powerful predictor of chronic stage LV dysfunction. 17) Their findings were in agreement with ours: the second BNP level, obtained 24 hours after admission, correlates better than BNP at baseline with echocardiographic parameters of LV systolic function. On the other hand, it is reasonable to assess BNP in asymptomatic patients with a previous history of myocardial infarction and a low ejection fraction.…”

Section: Discussionsupporting

confidence: 82%

“…9,16) We also believe that there is only one paper evaluating BNP in patients with first AMI. 17) There are several possible reasons why BNP measured later from the onset of AMI predicts a better outcome than the baseline sample. During the acute phase of AMI plasma, BNP levels initially rise within 24 hours and then gradually decrease (monophasic pattern) or show a secondary increase again at 5 to 7 days (biphasic pattern).…”

Section: Discussionmentioning

confidence: 99%

“…8) So far, only a few studies have assessed serial BNP measurements in ACS patients. 12,17) Talwar, et al demonstrated that measurements taken later during hospitalization had a greater value in prediction of poor LV function and a worse prognosis, than when it was estimated in the immediate postinfarction period. 12) It is our belief that this study is the first to indicate that both BNP measurements confirm the acute stage of LV dysfunction in patients with first AMI, while higher levels of BNP 24 hours later enable better selection of patients with a high in-hospital event rate risk.…”

Section: Discussionmentioning

confidence: 99%

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The Benefits of Repeated Measurements of B-type Natriuretic Peptide in Patients With First ST-Elevation Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention

Kuklinska¹,

Sobkowicz²,

Kamiński³

et al. 2006

Int. Heart J.

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SUMMARYBackground: Elevated B-type natriuretic peptide levels in patients with acute myocardial infarction are useful in the prediction of poor outcome. It is still not established how often and when assessment of neurohormonal activation provides the best prognostic information. Aim:To evaluate whether repeated measurements of B-type natriuretic peptide provide additional clinical information in patients with first ST-elevation myocardial infarction. Methods:In 96 consecutive patients with first ST-elevation myocardial infarction, treated with primary percutaneous coronary intervention, B-type natriuretic peptide concentrations were measured twice: on admission and 24 hours later. A clinical composite endpoint was assessed during hospital stay. Results:The median B-type natriuretic peptide concentration obtained on admission was 62.9 pg/mL and 24 hours later was 223.6 pg/mL. Thirty-five patients (36.4%) reached composite endpoint, including 3 deaths (3.1%). Both B-type natriuretic peptide levels were related to the clinical and echocardiographic variables, which refer to the large infarct expansion and acute left ventricular dysfunction. The first measurement was better correlated with current patient status (ie, TIMI Risk Score, admission Killip class). B-type natriuretic peptide 24 hours after admission was significantly higher in patients who had an adverse cardiovascular event during hospitalization (P = 0.02). ROC analysis also identified the second B-type natriuretic peptide measurement as significant to estimate adverse outcome (c = 0.64 CI 0.527 -0.756 P = 0.007). Conclusions:Despite there being a time interval of only 24 hours between the two sets of B-type natriuretic peptide sampling, both measurements provide important and different information. Only B-type natriuretic peptide measurement 24 hours after admission From the Departments of 1 Cardiology,

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Section: Discussionsupporting

confidence: 82%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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The Benefits of Repeated Measurements of B-type Natriuretic Peptide in Patients With First ST-Elevation Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention

Kuklinska¹,

Sobkowicz²,

Kamiński³

et al. 2006

Int. Heart J.

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“…Le NT-proBNP (pg/mL) a été évalué à un moment aléatoire, au bout de 24 h, puis de 72 h, la zone de créatine-kinase MB sous la courbe a été mesurée à molecules have been shown to confer powerful prognostic information in acute coronary syndromes (3,4), but there is limited information on the relationship of serial markers of the natriuretic system to STEMI. BNP (and NT-proBNP) rises quickly after the onset of infarction (5,6), and may be a marker of infarct-related artery (IRA) recanalization (7). However, the associations of tissue-level reperfusion, coronary artery flow and infarct size on BNP levels have not been adequately addressed.…”

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confidence: 99%

N-terminal pro-brain natriuretic peptide and the timing, extent and mortality in ST elevation myocardial infarction

Théroux

Chang

Mahaffey

et al. 2006

Canadian Journal of Cardiology

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“…27,30 The concept of coronary ischaemia causing BNP release was investigated by Tateishi, and also by Kyriakides, who found that the interruption of blood supply to myocardium during revascularisation procedures caused a temporary increase in BNP release, which subsequently returned to baseline within 24 hours. Interestingly, this has not been shown to be the case with ANP.…”

Section: -29mentioning

confidence: 99%

Review: The utility of BNP in clinical practice

Sharp

Mayet

2004

J Renin Angiotensin Aldosterone Syst

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Brain natriuretic peptide (BNP) is a cardiac neurohormone of increasing interest over recent years, with research applications expanding at a rapid rate and new data published on a monthly basis. Initially developed as a diagnostic aid for those with acute shortness of breath, clinical applications are now increasing, and this article reviews these clinical applications of BNP and the evidence for effectiveness of the synthetic BNP analogue nesiritide. BackgroundThe natriuretic peptides are a family of vasoactive vascular neurohormones whose role in cardiovascular homeostasis has been a subject of great interest in recent years. The two members of the family of most interest, atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP), have been extensively researched, with BNP in particular established as a useful clinical diagnostic and prognostic tool. This review will concentrate on BNP and review the myriad of uses it has taken on in the field of diagnostic chemical pathology, before looking at the role of the synthetic BNP analogue, nesiritide, in the treatment of cardiac failure.

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Early recanalization and plasma brain natriuretic peptide as an indicator of left ventricular function after acute myocardial infarction

Cited by 22 publications

References 25 publications

The Benefits of Repeated Measurements of B-type Natriuretic Peptide in Patients With First ST-Elevation Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention

The Benefits of Repeated Measurements of B-type Natriuretic Peptide in Patients With First ST-Elevation Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention

N-terminal pro-brain natriuretic peptide and the timing, extent and mortality in ST elevation myocardial infarction

Review: The utility of BNP in clinical practice

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