“…Keywords: direct oral anticoagulants, DOACs, anticoagulation, warfarin, vitamin K antagonists. For many years, the only oral anticoagulants (OACs) available world-wide were the vitamin K antagonists (VKAs) (Johnson et al, 2016), of which warfarin is the most commonly prescribed in the United Kingdom (Protty & Hayes, 2017). The direct oral anticoagulants (DOACs) offer an attractive alternative to VKAs and have a number of advantages, including: (i) no requirement for routine monitoring, (ii) fixed dosing, (iii) more predictable dose responses, (iv) no food interactions, and (v) fewer drug interactions (Baglin, 2013).…”