2016
DOI: 10.1016/j.ijrobp.2016.01.019
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Early Radiosurgery Improves Hearing Preservation in Vestibular Schwannoma Patients With Normal Hearing at the Time of Diagnosis

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Cited by 50 publications
(31 citation statements)
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“…The study found that patients in the early treatment group maintained serviceable hearing significantly longer than those patients in the late treatment group; 1-, 3-, 5-, and 10-year rates of serviceable hearing preservation were 96, 93, 88, and 64% for the early treatment group, compared with 87, 73, 55, and 55% for the late treatment group. 50 Limitations to this study include its retrospective nature and the fact that the late treatment group had slightly lower speech discrimination scores and significantly higher PTAs as compared with the early treatment group. Nevertheless, future studies exploring the role of radiation timing should be explored to better characterize this interesting finding.…”
Section: Timing Of Radiationmentioning
confidence: 94%
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“…The study found that patients in the early treatment group maintained serviceable hearing significantly longer than those patients in the late treatment group; 1-, 3-, 5-, and 10-year rates of serviceable hearing preservation were 96, 93, 88, and 64% for the early treatment group, compared with 87, 73, 55, and 55% for the late treatment group. 50 Limitations to this study include its retrospective nature and the fact that the late treatment group had slightly lower speech discrimination scores and significantly higher PTAs as compared with the early treatment group. Nevertheless, future studies exploring the role of radiation timing should be explored to better characterize this interesting finding.…”
Section: Timing Of Radiationmentioning
confidence: 94%
“…Akpinar and colleagues studied the effect of early treatment ( 2 years) versus late treatment (>2 years) of 88 VS patients with GR Class 1 hearing utilizing SRS. 50 Both cohorts received an average tumor margin dose of 12.5 Gy (range, 11.5-13 Gy) and had a median follow-up of 75 months (range, 12-169 months). The study found that patients in the early treatment group maintained serviceable hearing significantly longer than those patients in the late treatment group; 1-, 3-, 5-, and 10-year rates of serviceable hearing preservation were 96, 93, 88, and 64% for the early treatment group, compared with 87, 73, 55, and 55% for the late treatment group.…”
Section: Timing Of Radiationmentioning
confidence: 99%
“…is associated with higher rates of hearing deterioration compared to slower growing tumors 31 . If hearing preservation remains a treatment objective, earlier intervention may lead to a better outcome 52 .…”
Section: Observationmentioning
confidence: 99%
“…This is why important data show better hearing outcomes with earlier management, when hearing is at its highest level. 1 The concept of "watch and wait" for smaller tumors has been followed most commonly by tumor growth and hearing loss. 37 As for the use of low radiation doses, my personal concern is that a dose reduction may lead to a higher failure rate for longer-term tumor control without clear benefit to hearing.…”
Section: Vestibular Schwannomasmentioning
confidence: 99%