Early psychosis for the non-specialist doctor

Sami, Musa; Shiers, David; Latif, Saqib; Bhattacharyya, Sagnik

doi:10.1136/bmj.j4578

Cited by 8 publications

(6 citation statements)

References 37 publications

(41 reference statements)

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“…In the English-speaking world, many authorities are beginning to abandon the use of the term schizophrenia both in clinical practice and in the academic literature, and increasingly refer to the condition as psychosis (e.g. Sami et al 13 ). For example, the former Schizophrenia Bulletin recently changed title to Schizophrenia Bulletin: The Journal of Psychoses and Related Disorders in a bid to acknowledge the changing ideas about the diagnosis of schizophrenia 14 .…”

Section: Changing the Name Of Schizophreniamentioning

confidence: 99%

Using Twitter to assess attitudes to schizophrenia and psychosis

2019

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Aims and methodSchizophrenia is a psychotic disorder that is stereotypically stigmatised as untreatable and associated with violence. Several authorities have suggested that changing the name, for example to psychosis, would reduce such stigmatisation. We aimed to compare attitudes to schizophrenia and psychosis on Twitter to see if psychosis was associated with less negative attitudes. Tweets containing the terms ‘schizophrenia’, ‘schizophrenic’, ‘psychosis’ or ‘psychotic’ were collected on www.twitter.com and were captured with NCapture. On NVivo, tweets were coded into categories based on user type, tweet content, attitude and stigma type by two independent raters. We compared the content and attitudes of tweets referring to schizophrenia/schizophrenic and psychosis/psychotic.ResultsA total of 1120 tweets referring to schizophrenia/schizophrenic and 1080 referring to psychosis/psychotic were identified over two 7-day periods; 424 original tweets for schizophrenia and 416 original tweets for psychosis were included in the analysis. Psychosis was significantly more commonly included in tweets expressing negative attitudes (n=131, 31.5%) than schizophrenia (n=41, 9.7%) (χ² = 237.03, P < 0.0001). Of the personal opinions or dyadic interactions, 125 (53.4%) in the psychosis data set were stigmatising, compared with 33 (24.6%) of those in the schizophrenia set (χ² = 44.65, P < 0.0001).Clinical implicationsThe terms psychosis/psychotic are associated with a significantly higher number of tweets with negative content than schizophrenia/schizophrenic. Together with other evidence, this suggests that changing the name of schizophrenia to psychosis will not reduce negative attitudes toward the condition.Declaration of interestS.L. has received personal fees from Otsuka and Sunovion, and personal and research fees from Janssen.

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Section: Changing the Name Of Schizophreniamentioning

confidence: 99%

Using Twitter to assess attitudes to schizophrenia and psychosis

2019

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“…In recent years, more attention has been paid to the public health impact of cannabis use, especially by young adults (Hall and Lynskey, 2016) with evidence of a growing prevalence of regular cannabis use worldwide, with approximately 200 million users (National Academies of Sciences, 2017). Convergent and replicated findings indicate that cannabis use can induce psychotic symptoms (Henquet et al, 2005;Skinner et al, 2011;van Gastel et al, 2012) and increase the risk of developing a psychotic disorder (Colizzi and Murray, 2018;Moore et al, 2007;Radhakrishnan et al, 2014;Sami et al, 2017), especially in young and vulnerable individuals with a history of heavy use (Colizzi et al, 2015a;Colizzi et al, 2015b). This is in line with experimental evidence that acute administration of delta-9tetrahydrocannabinol (∆9-THC) as well as cannabinoid agonists, including phytocannabinoids and synthetic cannabinoids, induce transient psychosis-like symptoms and cognitive impairments in individuals at clinical high-risk to develop a psychotic disorder (Vadhan et al, 2017) as well as healthy individuals (Bhattacharyya et al, 2009;D'Souza et al, 2004;Sherif et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

Longitudinal assessment of the effect of cannabis use on hospital readmission rates in early psychosis: A 6-year follow-up in an inpatient cohort

Colizzi

Burnett

Costa

et al. 2018

Psychiatry Research

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Cannabis is the most commonly used illicit drug in psychosis patients and has been identified as a risk factor for relapse and subsequent hospital readmission, having substantial economic implications. To clarify the contribution of cannabis consumption to hospital readmission, a consecutive inpatient cohort of 161 early psychosis patients was included into the study. Data on cannabis use at admission and number of hospital readmissions and length of stay (LOS, number of inpatient days) in a 6-year follow-up was extracted from clinical notes. 62.4% of the patients had lifetime cannabis use. Their admission lasted on average 54.3 ± 75 days and over the following 6 years patients had 2.2 ± 2.8 hospital readmissions, for a total of 197.4 ± 331.5 days. Cannabis use significantly predicted the number of hospital readmissions and LOS in the following 6 years, the latter remaining significant after adjusting for use of other substance. Cannabis-using patients of male gender and Black ethnicity had a longer LOS at follow-up compared to female patients and other ethnic groups, respectively. Having a history of cannabis use when admitted to an early intervention inpatient unit for psychosis is associated with a higher number of subsequent hospital readmissions and a longer LOS, especially in male and Black patients.

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“…Kai kuriais atvejais, esant dideliam simptomų išreikštumui, individui gali formuotis prodrominė būsena ir atsirasti didelė psichozės pasireiškimo rizika. Tokiais atvejais svarbu įvertinti mąstymo, suvokimo, nuotaikos sutrikimus, įtariamus praeityje buvusius psichozės epizodus ir nukreipti pacientą gydytojo-psichiatro konsultacijai [7].…”

Section: Tyrimo Rezultataiunclassified

Ar Aplinkos Veiksnių Poveikis Gali Būti Siejamas Su Šizofrenijos Išsivystymu?

Grigas¹

2021

Health Sciences

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Tyrimo tikslas. Apžvelgti ir apibendrinti įrodymais grįstos medicinos duomenis apie šizofrenijos proceso vystymosi eigą, išorinės aplinkos veiksnių tikėtiną poveikį, simptomų raišką ir ankstyvo ligos atpažinimo galimybes bendrosios praktikos gydytojo darbe. Metodika. Atlikta teminių straipsnių paieška Pubmed, Cochrane, SpringerLink duomenų bazėse, naudojant reikšminius žodžius: šizofrenija, rizikos veiksniai, kanapės, ankstyvos vaikystės traumos, urbanizacija, D vitaminas, perinatalinė infekcija, bendrosios praktikos gydytojas (angl. schizophrenia,risk factors, cannabis, childhood trauma, urbanisation, vitamin D, perinatal infection, general practitioner). Iš daugiau nei 100 mokslinių publikacijų, atrinkta 30 straipsnių. Rezultatai. Apžvelgti su šizofrenijos išsivystymu susiję pagrindiniai rizikos veiksniai, simptomų raiška ir ligos išsivystymo modelis. Įvertintas išorinės aplinkos veiksnių ryšys su šizofrenijos išsivystymu. Išvados. Nustatyta, jog išorinės aplinkos veiksniai susiję su šizofrenijos išsivystymu. Kanapių vartojimas, ankstyvosios vaikystės traumos, urbanizacija susiję su padidėjusia šizofrenijos išsivystymo rizika ar stipriau išreikštais ligos simptomais. Stebimas padidėjęs ligos pasireiškimo dažnis tarp tų pacientų, kuriems buvo nustatyta sumažėjusi D vitamino koncentracija organizme, ar perinataliniu laikotarpiu pasireiškė infekcija.

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Early psychosis for the non-specialist doctor

Cited by 8 publications

References 37 publications

Using Twitter to assess attitudes to schizophrenia and psychosis

Using Twitter to assess attitudes to schizophrenia and psychosis

Longitudinal assessment of the effect of cannabis use on hospital readmission rates in early psychosis: A 6-year follow-up in an inpatient cohort

Ar Aplinkos Veiksnių Poveikis Gali Būti Siejamas Su Šizofrenijos Išsivystymu?

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