Early Prenatal Diagnosis of Choledochal Cyst

Gallivan, E. Kerry; Crombleholme, Timothy M.; D’Alton, Mary E.

doi:10.1002/(sici)1097-0223(199610)16:10<934::aid-pd961>3.0.co;2-4

Cited by 14 publications

(5 citation statements)

References 15 publications

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“…The occurrence of choledochal cysts in twins [41], in siblings, and their detection in utero [42,43] supports that, at least in some children, a genetic abnormality [44][45][46] leads to a developmental abnormality including biliary papillomatosis [47,48], leading to cyst formation in the developing fetus. The occurrence of choledochal cysts in twins [41], in siblings, and their detection in utero [42,43] supports that, at least in some children, a genetic abnormality [44][45][46] leads to a developmental abnormality including biliary papillomatosis [47,48], leading to cyst formation in the developing fetus.…”

Section: Pathophysiologymentioning

confidence: 99%

Biliary Disease in Infants and Children

Superina¹

2006

Diseases of the Gallbladder and Bile Ducts

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In judicandus ye are a physician, in curando, a surgeon. The patient asks for cure -surgery -and not for theory -medicine -it is the doctor who needs the latter. That is: there can be no surgeon who is not also a physician; the latter begets the surgeon and the surgeon tests the physician by the result of his work. Paracelsus O B J EC T I V E S• Become familiar with the diagnostic approach to the child with jaundice • Understand the pathogenesis and treatment strategies used in children with biliary atresia • Classify and discuss the treatment strategies in children with choledochal cysts • List the varying types of progressive familial intrahepatic cholestasis (PFIC)

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Section: Pathophysiologymentioning

confidence: 99%

Biliary Disease in Infants and Children

Superina¹

2006

Diseases of the Gallbladder and Bile Ducts

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“…Choledochal cysts are rarely encountered, occurring more frequently in Asian populations 2,24 . Sonographically, they usually present as a cyst in the right upper quadrant in the region of the porta hepatis, separate from the gallbladder and duodenum 2,24 . The diagnosis can be definitively made when bile ducts are seen in continuity with the cyst 1,24 .…”

Section: Rare Causes Of Foetal Abdominal Cystic Massesmentioning

confidence: 99%

“…(Fig. 14) A choledochal cyst might be identified in the early second trimester 24 . The differential diagnosis of an upper abdominal cyst includes duplication cyst, congenital hepatic cyst, gallbladder duplication, the distended duodenum of duodenal atresia and situs inversus, in which case the ‘cyst’ represents the abnormally sited stomach 2,3…”

Section: Rare Causes Of Foetal Abdominal Cystic Massesmentioning

confidence: 99%

“…Fusiform dilatation of the common bile duct is the most common choledochal cyst, and the type most frequently detected antenatally 2,25 . Intrauterine intervention is not required, but early postnatal surgery ameliorates complications of cholestasis, cholangitis, biliary cirrhosis and portal hypertension 24,25 …”

Section: Rare Causes Of Foetal Abdominal Cystic Massesmentioning

confidence: 99%

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Foetal cystic abdominal masses

McEwing

Hayward

Furness

2003

Australasian Radiology

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“…In the prenatal US, fetal CDCs have been described as follows: anechoic cysts located in the right upper quadrant of the abdomen, the subhepatic, or the region of the porta hepatis, with no septum, and these are connected to the gallbladder or hepatic ducts [ 7 ]. The latter two have always been considered as decisive signs in the prenatal diagnosis [ 8 ], but these could not be observed in all prenatal CDC cases [ 9 ], and the accuracy for the prenatal diagnosis of CDCs is only 7.7% [ 10 ]. Fetal CDCs may be misdiagnosed as origin-uncertain abdominal cysts, duodenal atresia, hepatic cysts, ovarian cysts, mesenteric cysts, renal abnormalities, normal gallbladder, or situs inversus [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

Accuracy of Magnetic Resonance Imaging in Prenatal Diagnosis of Choledochal Cysts: A Single-Center Retrospective Analysis

Jinsheng

et al. 2022

International Journal of Clinical Practice

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Background. The purpose of this study is to evaluate the accuracy of prenatal MRI in diagnosing choledochal cysts (CDC), evaluate the sensitivity and specificity of MRI signs in the diagnosis of fetal CDC, and first compare the trend of size of CC between prenatal and postpartum. Methods. A total of 18 fetal who were diagnosed with CDCs through prenatal MRI were enrolled in the study. We summarized and analyzed the prenatal clinical data and prognosis information of prenatal and postpartum surgery, then compared the sensitivity, specificity, and diagnostic accuracy of various signs of MRI and postpartum MRCP diagnosis of CC. Finally, we tried to compare the earliest prenatal detection of common bile duct cysts with the size of surgery, and calculated the growth rate of common bile duct cysts for the first time. Results. All 18 patients were delivered in our institution. Among these patients, 14 were confirmed with CDCs after postpartum surgery, two patients had CDCs that disappeared, and two patients were confirmed with cystic biliary atresia (CBA) through the Kasai operation. Furthermore, 13 patients with CDCs and two patients with CBA underwent MRCP before the operation, and one patient with CDCs ruptured at birth and underwent ultrasound diagnosis. The sensitivity and diagnostic compliance of prenatal MRI signs for the location were higher when compared to postnatal MRCP (100% vs. 76.9% and 83.3% vs. 66.7%): the cyst was located at the porta hepatis, which was higher than the lowest edge of the liver, and parallel to the hepatoduodenal ligament. Conclusion. Prenatal MRI is higher than that of US for diagnosing CDCs, specifically in identifying the location of the cyst and confirming the origin of the cyst. The length, width, and size of the CDC become slightly bigger in our study.

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Early Prenatal Diagnosis of Choledochal Cyst

Cited by 14 publications

References 15 publications

Biliary Disease in Infants and Children

Biliary Disease in Infants and Children

Foetal cystic abdominal masses

Accuracy of Magnetic Resonance Imaging in Prenatal Diagnosis of Choledochal Cysts: A Single-Center Retrospective Analysis

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