2001
DOI: 10.1097/00006254-200101000-00011
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Early Predictors of Adverse Outcome in Term Infants With Post-Asphyxial Hypoxic Ischemic Encephalopathy

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“…There is an ongoing discussion on prediction of asphyxial sequelae. Fetal heart rate patterns, need of resuscitation, umbilical arterial blood gas analysis, and Apgar scores showed variable predictive values (21)(22)(23)(24)(25), most likely due to the nonhomogeneity of the studied populations. Toh (23) reported a positive predictive value of 100% for either death or major neurologic disability using a combination of a 5-min Apgar score Ͻ4 and arterial blood base deficit of more than 20 mM within 2 h after birth.…”
Section: Discussionmentioning
confidence: 96%
“…There is an ongoing discussion on prediction of asphyxial sequelae. Fetal heart rate patterns, need of resuscitation, umbilical arterial blood gas analysis, and Apgar scores showed variable predictive values (21)(22)(23)(24)(25), most likely due to the nonhomogeneity of the studied populations. Toh (23) reported a positive predictive value of 100% for either death or major neurologic disability using a combination of a 5-min Apgar score Ͻ4 and arterial blood base deficit of more than 20 mM within 2 h after birth.…”
Section: Discussionmentioning
confidence: 96%
“…Auch ein Nabelarterien-pH ist nur bedingt als prognostisches Kriterium zu verwerten [45]. Eine hohe Spezifität hinsichtlich Morbidität und Mortalität wird bei Reifgeborenen mit hypoxisch-ischämischer Enzephalopathie ermittelt, wenn ein 5¢-Apgar-Wert < 4 mit einen NapH < 7,1 oder BE > ± 20 einhergeht [54]. Sonographische und dopplersonographische Zeichen eines Hirnödems mit nachfolgender Hirnatrophie fanden wir ebenfalls bei den reiferen Neugeborenen (³ 33 SSW) mit perinataler Asphyxie (NapH £ 6,9).…”
Section: Abstract Cerebral Palsy´ultrasound´risk Factorsunclassified