Early Postoperative Insulin-Resistance Changes After Sleeve Gastrectomy

Rizzello, Mario; Abbatini, Francesca; Casella, Giovanni; Alessandri, Giorgio; Fantini, A; Leonetti, Frida; Basso, Nicola

doi:10.1007/s11695-009-0017-2

Cited by 119 publications

(82 citation statements)

References 39 publications

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“…Obesity is a major risk factor for developing diabetes, with relative risk of 5% in men and 8-20% in women 34,35 . The resolution of type II diabetes consequent to the sleeve gastroplasty is described by Cottan et al and Silecchia et al, respectively, as 81% 36 and 79.6% 37 .…”

Section: Discussion Discussion Discussion Discussionmentioning

confidence: 99%

Avaliação da qualidade de vida tardia após gastroplastia vertical

Pimenta

Moura

Filho³

et al. 2013

Rev. Col. Bras. Cir.

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Long-term quality of life after vertical sleeve gastroplasty Long-term quality of life after vertical sleeve gastroplasty Long-term quality of life after vertical sleeve gastroplasty Long-term quality of life after vertical sleeve gastroplasty Long-term quality of life after vertical sleeve gastroplasty We conducted a historical cohort study including patients with morbid obesity the in the Unified Health System (SUS), registered in the database of the General University Hospital, University of Cuiabá. All patients underwent vertical sleeve gastroplasty and were followed for at least one year after the operation. The study variables were: quality of life, weight loss, improvement of hypertension and diabetes, and mortality. Results Results ResultsResults Results: The sample comprised 41 patients, 13 (31.7%) men and 28 (61.3%) women, mean age was 37 years, the average weight was 136.4 kg and mean BMI 50.3 kg/m 2 ; mean follow-up was 19.1 months (12-32). There was a significant reduction in weight (96.7 kg, p < 0.001) and BMI (35.835 kg/m 2 , p < 0.001). The rate of blood pressure decreased from 56% to 31.7%, and diabetes from 14.6% to 4.8% (p < 0.001). Quality of life improved in 92.5% of patients. ConclusionConclusion Conclusion Conclusion Conclusion: There was an improvement in the quality of life in the majority of patients, achieved by means of weight loss and clinical improvement of diabetes and hypertension.

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Section: Discussion Discussion Discussion Discussionmentioning

confidence: 99%

Avaliação da qualidade de vida tardia após gastroplastia vertical

Pimenta

Moura

Filho³

et al. 2013

Rev. Col. Bras. Cir.

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“…Acute caloric restriction causes some, but not a comparable improvement in obese controls with T2D undergoing laparoscopic cholecystectomy (163), and thus is not the primary mechanism. Furthermore, foregut exclusion plays no mechanistic role in LSG.…”

Section: Mechanisms Of Weight Loss After Lsgmentioning

confidence: 96%

Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy: understanding weight loss and improvements in type 2 diabetes after bariatric surgery

Scott

Batterham

2011

American Journal of Physiology-Regulatory, Integrative and Comp

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Obesity increases the likelihood of diseases like type 2 diabetes (T2D), heart disease, and cancer, and is one of the most serious public health problems of this century. In contrast to ineffectual prevention strategies, lifestyle modifications, and pharmacological therapies, bariatric surgery is a very effective treatment for morbid obesity and also markedly improves associated comorbidities like T2D. However, weight loss and resolution of T2D after bariatric surgery is heterogeneous and specific to type of bariatric procedure performed. Conventional mechanisms like intestinal malabsorption and gastric restriction do not fully explain this, and potent changes in appetite and the enteroinsular axis, as a result of anatomical reorganization and altered hormonal, neuronal, and nutrient signaling, are the portended cause. Uniquely these signaling changes appear to override vigorous homeostatic defenses of stable body weight and compelling self-gratifying motivations to eat and to reverse defects in beta-cell function and insulin sensitivity. Here we review mechanisms of weight loss and T2D resolution after Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy bariatric surgery, two markedly different procedures with robust clinical outcomes.

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“…It is known that bariatric surgery can have an acute glycaemic effect: as short as 48 hours after the operation, the patients are known to have improved blood glucose levels 3,23,24,25 . Hence bariatric surgery has been coined as a "surgical treatment for diabetes" 26 .…”

Section: Introductionmentioning

confidence: 99%

Early Effect of Bariatric Surgery on Urogenital Function in Morbidly Obese Men

Al-Eid

Muneer

Renshaw

et al. 2017

The Journal of Sexual Medicine

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Running head: Early effect of bariatric surgery on ED and LUTSKeywords: bariatric surgery, weight loss, erectile dysfunction, lower urinary tract symptoms, body mass index 2 Abstract:Introduction: Obesity is an independent risk factor for erectile dysfunction (ED) and lower urinary tract symptoms (LUTS). Bariatric surgery has been shown to improve erectile function and urinary symptoms in previous medium to long term studies (3-12 months post-operative follow up).

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Early Postoperative Insulin-Resistance Changes After Sleeve Gastrectomy

Abstract: After SG the improvement of insulin action occurred rapidly and independently of EWL. The results of the present study confirm that a hormonal mechanism may contribute to changes in insulin resistance following SG.

Cited by 119 publications

References 39 publications

Avaliação da qualidade de vida tardia após gastroplastia vertical

Avaliação da qualidade de vida tardia após gastroplastia vertical

Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy: understanding weight loss and improvements in type 2 diabetes after bariatric surgery

Early Effect of Bariatric Surgery on Urogenital Function in Morbidly Obese Men

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