Early Peri-Operative Glycaemic Control and Allograft Rejection in Patients With Diabetes Mellitus: A Pilot Study

Thomas, Merlin C.; Mathew, Timothy H.; Russ, Graeme R.; Rao, M. Mohan; Moran, John L.

doi:10.1097/00007890-200110150-00024

Cited by 100 publications

(52 citation statements)

References 7 publications

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“…Most studies have reported that transplant patients with hyperglycemia and PTDM after transplantation have higher rates of rejection, infection, and rehospitalization (100,102,107).…”

Section: Posttransplantation Diabetes Mellitusmentioning

confidence: 99%

2. Classification and Diagnosis of Diabetes:Standards of Medical Care in Diabetes—2018

2017

Diabetes Care

2,573

1,223

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The American Diabetes Association (ADA) “Standards of Medical Care in Diabetes” includes ADA’s current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA’s clinical practice recommendations, please refer to the Standards of Care Introduction. Readers who wish to comment on the Standards of Care are invited to do so at professional.diabetes.org/SOC.

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“…Most studies have reported that transplant patients with hyperglycemia and PTDM after transplantation have higher rates of rejection, infection, and rehospitalization (100,102,107).…”

Section: Posttransplantation Diabetes Mellitusmentioning

confidence: 99%

2. Classification and Diagnosis of Diabetes:Standards of Medical Care in Diabetes—2018

2017

Diabetes Care

2,573

1,223

View full text Add to dashboard Cite

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“…Thomas et al [27] [30], изучая функцию почечного аллотрансплантата (ПАТ), выяснили, что сни-жение его функции в двух группах достоверно не различалось; однако 5-летняя выживаемость трансплантата у пациентов с ПТСД составила 70% по сравнению с 90% у больных без СД. Также выявлено, что инфекции были главным осложне-нием в группе с ПТСД и составили 53% по сравне-нию с 16% в контрольной группе.…”

Section: Review Articles and Lecturesunclassified

The causes of development and methods of correction of post-transplant diabetes mellitus

Лазарева¹,

Ржевская²,

Загородникова³

2017

Transplantologiâ (Mosk.)

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“…Bei Nierentransplantation war das Risiko einer Abstoßung fast verdoppelt, wenn bei Aufnahme nach der Operation die Glukosewerte über 110 mg/dl erhöht waren [14]. Das Phäno-men war ähnlich ausgeprägt bei Diabetikern [15].…”

Section: Prognostische Bedeutung Der Hyperglykämieunclassified

Perioperative Hyperglykämie

Hiesmayr¹

2004

Visc Med

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Perioperative Hyperglycaemia Hyperglycaemia is frequently observed during acute illness and after surgery or admission to an intensive care unit. It is observed twice as frequently in diabetic patients than in non-diabetics. The relative risk of a poor outcome is 1.5–6 in patients with ‘stress-hyperglycaemia’. Acute hyperglycaemia induces pathophysiologic changes with consequences even several hours to days after exposure. Hyperglycaemia modifies the function of leucocytes, monocytes, platelets and immunglobulins. Perfusion is reduced, most severely after ischaemia. The area of myocardial infarction is enlarged and prognosis after cerebral ischaemia worsened. In addition hyperglycaemia reduces gastro-intestinal motility. Acute hyperglycaemia is also associated with more frequent rejection episodes after kidney transplantation. The continuous infusion of insulin improved outcome after myocardial infarction, cardiac surgery and burns as well as in intensive care patients. The aim of insulin therapy is to normalise blood sugar levels early after injury.

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Early Peri-Operative Glycaemic Control and Allograft Rejection in Patients With Diabetes Mellitus: A Pilot Study

Abstract: This pilot study suggests that hyperglycemia may be associated with an increased risk of both allograft rejection and postoperative infection in patients with diabetes.

Cited by 100 publications

References 7 publications

2. Classification and Diagnosis of Diabetes:Standards of Medical Care in Diabetes—2018

2. Classification and Diagnosis of Diabetes:Standards of Medical Care in Diabetes—2018

The causes of development and methods of correction of post-transplant diabetes mellitus

Perioperative Hyperglykämie

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