Early outcomes after transoral CO₂ laser resection of laryngeal and hypopharyngeal squamous cell carcinoma: one centre's experience

Abstract

Objectives: To review early oncological outcomes following transoral CO 2 laser resection of laryngeal and hypopharyngeal squamous cell carcinoma.Design: Retrospective review of hospital electronic database. Setting: Large district general hospital in England, UK. Main outcome measures: Patients' three-year disease-specific survival and disease-free survival were evaluated, including post-operative complications, voice quality and swallowing status.Results: Seventy-seven patients (16 women and 61 men) were identified. Transoral laser excision of squamous cell carcinoma of the larynx was undergone by 65 patients, and the same procedure in the hypopharynx by 12. Patients with laryngeal cancer had statistically better disease-specific survival than those with hypopharyngeal cancer ( p ¼ 0.021), although the cumulative disease-free survival probability was 0.71 for both larynx and hypopharynx groups. Patients who underwent laryngectomy following failed laser treatment or as a salvage procedure had poorer outcomes.Conclusions: The overall results of this study were comparable with those of other, larger studies. At three-year follow up, cumulative disease-specific survival probabilities were 0.92 and 0.71 for laryngeal and hypopharyngeal squamous cell carcinoma, respectively.

The Emerging Role of Robotic Surgery among Minimally Invasive Surgical Approaches in the Treatment of Hypopharyngeal Carcinoma: Systematic Review and Meta-Analysis

“…A nasogastric tube was necessary in 22 patients, and tracheotomy was performed in 14 patients. Comparable results were obtained by Leong et al [19] in 11 patients, of which 76% were alive at the last clinic review. One of the surviving patients needed a permanent percutaneous gastrostomy.…”

“…A total of 73 studies were screened for abstract evaluation. Of these, 17 were reviewed for full text, and 15 were finally included in the systematic review [8,9,10,11,12,13,14,15,16,17,18,19,20,21,22] (Table 1). All the included studies were retrospective or prospective observational studies.…”

“…Five of the included studies evaluated TORS [8,9,12,14,15], while ten studies focused on TLM [10,11,13,16,17,18,19,20,21,22] for the treatment of early or advanced stage hypopharyngeal cancer.…”