“…Considering AVR, we found a difference in the general estimation of the effect of postoperative pain in RCTs [ 8 - 12 ] , favoring MICS (SMD 0.87 [95% CI 0.04 to 1.71], P =0.04) ( Figure 2 ). However, in the sensitivity analysis, using the mean of the means and the square root of the mean of variances divided by the number of measurements, there was no difference between the groups (SMD 0.70 [95% CI -0.69 to 2.09], P =0.32) ( Figure 3 ).…”