Search citation statements
Paper Sections
Citation Types
Year Published
Publication Types
Relationship
Authors
Journals
Background and Objectives:Primary percutaneous coronary intervention (PCI) has been found to be superior, in terms of hospital mortality and long-term follow-up, compared with thrombolytic therapy for acute myocardial infarction (AMI). However, the clinical benefits of primary PCI have not been precisely evaluated in elderly patients. Subjects and Methods:Two hundred and twenty three patients (Group I: n=66, age≥75 years, Group II: n=157, age<75 years), who underwent primary PCI for AMI at Chonnam National University Hospital, between 2000 and 2002, were analyzed according to their clinical, angiographic characteristics, inhospital and one-year survival. Results:Group I had a higher percentage of women (45.5% vs. 19.1%, p= 0.00), multi-vessel disease (42% vs. 28%, p=0.031), right coronary artery disease (52% vs. 33%, p=0.021), and more frequent histories of diabetes mellitus (35% vs. 22%, p=0.039) and less smoking (38% vs. 60%, p= 0.003) than Group II. Successful reperfusion by PCI was achieved in 97 and 96 %, respectively (p=NS). The rates of in-hospital mortality were similar in both groups (12.1% vs. 8.2%, p=NS). There were no significant differences in the major adverse cardiac events between the two groups during the one-year clinical p=NS). Conclusion:Primary PCI in AMI patients older than 75 years can be performed with comparable procedural success rates and long-term clinical outcomes to those of younger patients. (Korean Circulation J 2005;35:613-619) KEY WORDS:Elderly;Myocardial infarction;Angioplasty. 서 론 최근에 급성 심근경색증 환자에서 혈전용해제보다 일차적 경피적 관상동맥 중재술(PCI: percutaneous coronary intervention)이 단기적 및 장기적 임상 효과가 좋음이 보고 되고 있으며, 1-4) 2004년 American College of Cardiology/ 논문접수일:2005년 3월 02일 심사완료일:2005년 5월 23일 교신저자:정명호, 501-757 광주광역시 동구 학1동 8번지 전남대학교 의과대학 전남대학교병원 심장센터, 의과학연구소 전화:(062) 220-6243·전송:(062) 228-7174·E-mail:myungho@chol.com
Background and Objectives:Primary percutaneous coronary intervention (PCI) has been found to be superior, in terms of hospital mortality and long-term follow-up, compared with thrombolytic therapy for acute myocardial infarction (AMI). However, the clinical benefits of primary PCI have not been precisely evaluated in elderly patients. Subjects and Methods:Two hundred and twenty three patients (Group I: n=66, age≥75 years, Group II: n=157, age<75 years), who underwent primary PCI for AMI at Chonnam National University Hospital, between 2000 and 2002, were analyzed according to their clinical, angiographic characteristics, inhospital and one-year survival. Results:Group I had a higher percentage of women (45.5% vs. 19.1%, p= 0.00), multi-vessel disease (42% vs. 28%, p=0.031), right coronary artery disease (52% vs. 33%, p=0.021), and more frequent histories of diabetes mellitus (35% vs. 22%, p=0.039) and less smoking (38% vs. 60%, p= 0.003) than Group II. Successful reperfusion by PCI was achieved in 97 and 96 %, respectively (p=NS). The rates of in-hospital mortality were similar in both groups (12.1% vs. 8.2%, p=NS). There were no significant differences in the major adverse cardiac events between the two groups during the one-year clinical p=NS). Conclusion:Primary PCI in AMI patients older than 75 years can be performed with comparable procedural success rates and long-term clinical outcomes to those of younger patients. (Korean Circulation J 2005;35:613-619) KEY WORDS:Elderly;Myocardial infarction;Angioplasty. 서 론 최근에 급성 심근경색증 환자에서 혈전용해제보다 일차적 경피적 관상동맥 중재술(PCI: percutaneous coronary intervention)이 단기적 및 장기적 임상 효과가 좋음이 보고 되고 있으며, 1-4) 2004년 American College of Cardiology/ 논문접수일:2005년 3월 02일 심사완료일:2005년 5월 23일 교신저자:정명호, 501-757 광주광역시 동구 학1동 8번지 전남대학교 의과대학 전남대학교병원 심장센터, 의과학연구소 전화:(062) 220-6243·전송:(062) 228-7174·E-mail:myungho@chol.com
Background and Objectives:In this current era of using drug-eluting stents (DES), studies that demonstrate the feasibility and clinical outcome of percutaneous coronary intervention (PCI) using DES in a subset of extremely aged patients are lacking. We investigated the clinical characteristics, therapeutic and clinical outcomes of patients older than 80 years that had been implanted with DES during a PCI. Subjects and Methods: Fifty-three "octogenarian" patients (≥80-years-old) and 1036 "non-octogenarian" patients (<80-years-old) that had been implanted with DES at Chonbuk National University Hospital since March 2003 were enrolled in the study. Medical records of the patients in the two groups were retrospectively reviewed. Results: The mean ages of the patients in the two groups were 83±2 years and 62±11 years, respectively, and the mean follow-up period was 15.8±10.9 months and 21.1±10.8 months, respectively. The octogenarian group showed an increased prevalence of female patients (58.5% vs. 35.1%, p=0.001), acute coronary syndrome (98.1% vs. 78.6%, p=0.001), ST-segment elevation myocardial infarction (41.5% vs. 28.3%, p=0.003), shock (17.0% vs. 6.6%, p=0.004), heart failure (22.6% vs. 9.3%, p=0.002) and a higher in-hospital major adverse cardiac event (MACE) rate (13.2% vs. 3.5%, p=0.004) than the non-octogenarian patients. Angiographic restenosis and target lesion revascularization rates were not different in both groups, but overall MACE (18.9% vs. 9.9%, p=0.035) and all-cause mortality (p<0.001) rates were significantly higher in the octogenarian group of patients. Conclusion: Although angiographic followup results were comparable in octogenarians and non-octogenarians, the occurrence of short-and long-term MACE was significantly higher in the very elderly group owing to a substantial subset of high-risk patients. (Korean
Background and Objectives:Acute myocardial infarction (AMI) at a young age less than 40 years is an uncommon condition and it is characterized by multiple cardiovascular risk factors. We analyzed the risk factors of restenosis in AMI patients who underwent percutaneous coronary intervention (PCI), and these patients were under the age of 40 years. Subjects and Methods:Between January 1997 and December 2006, 88 out of the 121 young AMI patients (mean age: 35.6±4.0 years, 115 males) who underwent follow-up coronary angiography after PCI were divided into two groups: the patients without restenosis (group I: n=62, mean age: 35.6±3.9 years, 60 males) and the patients with restenosis (group II: n=26, mean age: 36.3±3.8 years, 23 males). The clinical and coronary angiographic characteristics were compared between the two groups. Results:Smoking (79.3%) was the most common risk factor in all the patients. The baseline clinical characteristics and baseline laboratory findings were not different between the two groups. There was no significant difference in the sex ratio (p=0.124). The Thrombolysis In Myocardial Infarction (TIMI) flows were not different between the two groups. The level of homocysteine (hcy) was significantly decreased from 12.4±8.8 μmol/L to 9.3±3. 8 μmol/L in group I (p=0.011), but this was not changed significantly in group II (p=0.062). According to multiple logistic regression analysis, a high triglyceride level (>200 mg/dL) was an independent predictor of restenosis (p=0.046). Conclusion:A high level of serum triglyceride is a predictive factor of restenosis after PCI in young age patients with acute myocardial infarction.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.