Early onset of organ failure is the best predictor of mortality in acute pancreatitis

Prim, I. Poves; Prous, J. Fabregat; Borobia, Francisco Javier García; Jorba, Rosa; Felip, Juan Figueras; Mas, Emmanuel

doi:10.4321/s1130-01082004001000005

Cited by 22 publications

(4 citation statements)

References 28 publications

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“…Recent studies have focused on the role of intraabdominal hypertension (IAH)/abdominal compartment syndrome (ACS) in patients of SAP in ICU [29,30]. Numerous studies have found an association between IAH and the development of multiple organ dysfunction, leading to higher mortality [19,31]. IAP was significantly raised in nonsurvivors, similar to another study [32].…”

Section: Intraabdominal Pressuresupporting

confidence: 61%

Audit of patients with severe acute pancreatitis admitted to an intensive care unit

Singh

Poddar

Baronia

et al. 2012

Indian J Gastroenterol

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Section: Intraabdominal Pressuresupporting

confidence: 61%

Audit of patients with severe acute pancreatitis admitted to an intensive care unit

Singh

Poddar

Baronia

et al. 2012

Indian J Gastroenterol

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“…According to the Atlanta Classification, SAP can be divided into two phases. The first phase of about 7–10 days start with aseptic inflammation, systemic inflammation response syndrome (SIRS), sepsis, multi organs failure (MOF), and even death [21]. The second phase usually after the second week of the disease, the circumscribed complications such as pancreatic necrosis began to appear.…”

Section: Discussionmentioning

confidence: 99%

Parenteral Nutrition Combined with Enteral Nutrition for Severe Acute Pancreatitis

Singh

Chen

et al. 2012

ISRN Gastroenterology

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Background and Aims. Nutritional support in severe acute pancreatitis (SAP) is controversial concerning the merits of enteral or parenteral nutrition in the management of patients with severe acute pancreatitis. Here, we assess the therapeutic efficacy of gradually combined treatment of parenteral nutrition (PN) with enteral nutrition (EN) for SAP. Methods. The clinical data of 130 cases of SAP were analyzed retrospectively. Of them, 59 cases were treated by general method of nutritional support (Group I) and the other 71 cases were treated by PN gradually combined with EN (Group II). Results. The APACHE II score and the level of IL-6 in Group II were significantly lower than Group I (P < 0.05). Complications, mortality, mean hospital stay, and the cost of hospitalization in Group II were 39.4 percent, 12.7 percent, 32 ± 9 days, and 30869.4 ± 12794.6 Chinese Yuan, respectively, which were significantly lower than those in Group I. The cure rate of Group II was 81.7 percent which is obviously higher than that of 59.3% in Group I (P < 0.05). Conclusions. This study indicates that the combination of PN with EN not only can improve the natural history of pancreatitis but also can reduce the incidence of complication and mortality.

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“…End-stage organ failure is a serious condition associated with an increased risk of mortality ( 8 , 9 ). Organ transplantation is often the only treatment for patients with end-stage organ failure.…”

Section: Introductionmentioning

confidence: 99%

Psychological Distress and Its Association With Quality of Life in Organ Transplant Recipients During COVID-19 Pandemic

Cai

Song

et al. 2021

Front. Psychiatry

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Objectives: The coronavirus disease 2019 (COVID-19) pandemic may have an impact on the psychological distress of organ transplant recipients. We aimed to assess the status of psychological distress and its association with quality of life (QoL) in organ transplant recipients during the COVID-19 pandemic.Materials and Methods: A cross-sectional survey was carried out with 305 organ transplant recipients during March 30 and April 2, 2020, in Wuhan. Psychological distress comprised depression, anxiety, insomnia, and post-traumatic stress disorder (PTSD), which were assessed using the Patient Health Questionnaire-9, the seven-item Generalized Anxiety Disorder questionnaire, the Insomnia Severity Index, and Impact of event scale-revised. QoL was assessed using the Chinese version of the short Form 36-item health survey.Results: The prevalence of depression, anxiety, insomnia, and PTSD in organ transplant recipients was 13.4, 6.9, 11.8, and 30.5%, respectively. Organ transplant recipients with depression had significantly lower scores in all eight dimensions of QoL compared with participants without depression (all p < 0.05). Lower scores on the QoL dimensions of role physical, bodily pain, general health, vitality, role emotional, and mental health were found in organ transplant recipients with anxiety, insomnia, or PTSD compared with their counterparts without the respective disorder (all p < 0.05).Limitation: The cross-sectional study design limited us to make causal conclusion and the influence of potential confounders cannot be ruled out.Conclusions: Psychological distress was prevalent in organ transplant recipients during the COVID-19 pandemic, and those with depression, anxiety, insomnia, and PTSD had poorer QoL. Therefore, timely psychological counseling, COVID-19 related health education, and essential community medical services should be provided to organ transplant recipients to relieve their psychological distress, and to improve their QoL.

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Early onset of organ failure is the best predictor of mortality in acute pancreatitis

Cited by 22 publications

References 28 publications

Audit of patients with severe acute pancreatitis admitted to an intensive care unit

Audit of patients with severe acute pancreatitis admitted to an intensive care unit

Parenteral Nutrition Combined with Enteral Nutrition for Severe Acute Pancreatitis

Psychological Distress and Its Association With Quality of Life in Organ Transplant Recipients During COVID-19 Pandemic

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