Early Onset of Obesity and Adult Onset of Obesity as Factors Affecting Patient Characteristics Prior to Bariatric Surgery

Abstract

BackgroundPatients who are slated for bariatric surgery vary in terms of their age at onset of obesity, duration of obesity, and their health complications. Therefore, we aimed to explore a relationship between the age at onset of obesity, metabolic parameters, and health problems in bariatric surgery candidates.MethodsA total of 469 unrelated adults with obesity prior to bariatric surgery were included in this study. The study group consisted of 246 individuals who became obese < 20 years of age, and 223 individuals who became obese ≥ 20 years. Clinical, biochemical, anthropometric assessments, and DXA-derived measures were taken.ResultsPatients with early onset of obesity had a higher total body fat mass, and higher body fat percentage, and a 1.84 times higher risk of BMI above 40 kg/m2 than patients with adult onset of obesity (≥ 20 years). Multivariable logistic regression demonstrated that, among bariatric surgery candidates with early onset of obesity, the frequency of hypertension and type 2 diabetes was significantly lower than that in cases with an adult onset of obesity, despite a longer duration of obesity and higher BMI.ConclusionsThe age at which an individual reaches obesity has a significant impact on patient characteristics on the day he or she is evaluated for bariatric surgery. A younger age at obesity onset is a predicting factor for a higher BMI in patients, but they are less likely to clinically manifest well-established consequences of obesity, such as diabetes or hypertension, compared to patients with adult onset of obesity.

The Impact of Obesity on Nighttime Blood Pressure Dipping

“…Additionally, these groups differed in terms of metabolism: group 1 had statistically significantly higher HDL and lower TC levels (51.5 mg/dL and121 mg/dL vs. 44 mg/dL and 147 mg/dL, p = 0.05, respectively). This tendency was consistent with the observations of other researchers dealing with the qualification of patients for bariatric procedures [ 14 , 15 ]. According to an interesting meta-analysis, metabolic syndrome, including all or almost all its potential components (4 or 5 out of 5), is associated with earlier and more serious organ damage, at both cardiac and vascular levels [ 16 ].…”

“…ABPM plays a special role in the treatment of obese patients, in whom a significant clinical association between nocturnal change in BP and the risk of cardiovascular events was demonstrated [ 11 , 12 ]. Of significance are also correlations between BP values, BMI and the detrimental changes in cardiac structure, such as myocardial hypertrophy and left atrial enlargement, which may indicate early stages of elevated left ventricular filling pressure [ 13 , 14 ]. In the study group of 128 patients with obesity and BMI of at least 30 kg/m 2 , who had been considered as candidates for bariatric surgery, 2 sub-groups were identified: patients with class 1 and 2 obesity (group 1 with BMI 30–39 kg/m 2 ) and patients with class 3 obesity (group 2 with BMI ≥ 40 kg/m 2 ).…”

A study of affect regulation in obesity in egypt

“…These finding came in accordance with that of Wrzosek et al, (2018) who found that patients with early onset of obesity had a higher total body fat mass, and higher body fat percentage, and a 1.84 times higher risk of BMI above 40 kg/m2 than patients with adult-onset of obesity (≥ 20 years) [6].…”

Elective and nonelective cesarean section and obesity among young adult male offspring: A Swedish population–based cohort study

“…The attenuation by age could potentially explain our findings. However, childhood obesity not persisting into young adulthood or adulthood may be of less relevance for clinical manifestation of obesity-related consequences [65–67].…”