Early neuropsychological dysfunction in elderly high-risk patients after on-pump and off-pump coronary bypass surgery

Baba, Tomoko; Gotō, Tomoko; Maekawa, Kengo; Ito, Asuka; Yoshitake, Atushi; Koshiji, Takaaki

doi:10.1007/s00540-007-0538-6

Cited by 18 publications

(18 citation statements)

References 31 publications

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“…Twelve articles reported on hypercholesterolaemia. Of these, one used a combination of self-report and medical history for definition,19 four used laboratory measurements (total cholesterol ≥240 mg/dL23; total cholesterol ≥240 mg/dL and/or triglycerides≥150 mg/dL33; total cholesterol ≥200 mg/dL and/or medication29 30) and seven used the terms ‘hypercholesterolaemia’ or ‘hyperlipidaemia’ without definition 20 21 31 32 34–36. Eight articles reported on statin use 18 22 26–30.…”

Section: Resultsmentioning

confidence: 99%

Associations of dyslipidaemia and lipid-lowering treatment with risk of postoperative cognitive dysfunction: a systematic review and meta-analysis

Feinkohl

Winterer

Pischon

2018

J Epidemiol Community Health

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Section: Resultsmentioning

confidence: 99%

Associations of dyslipidaemia and lipid-lowering treatment with risk of postoperative cognitive dysfunction: a systematic review and meta-analysis

Feinkohl

Winterer

Pischon

2018

J Epidemiol Community Health

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“…Baba, et al 39) conducted a prospective study in 218 patients who underwent elective OPCAB (n = 89) or on-pump CABG (n = 129). Four cognitive tests were performed preoperatively and at 1 week postoperatively.…”

Section: Perioperative Neuropsychological Dysfunctionmentioning

confidence: 99%

Off-Pump Coronary Artery Bypass Grafting Revisited: Experience and Evidence from Japan

Doi

Okawa

2013

ATCS

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Off-pump coronary artery bypass grafting (OPCAB) is performed in about 65% of patients who require surgical coronary revascularization, and has become the standard procedure in coronary artery bypass grafting (CABG) in Japan. As a background of the high rate of OPCAB, many clinical and experimental studies have been performed and reported in Japan. In this review, several factors associated with OPCAB are discussed based on relevant and important clinical studies published in Japan in the English language.

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“…Investigators have evaluated whether or not differences in POCD exist between patients exposed to CPB and those not exposed during cardiac surgery. The results are inconclusive with some suggesting greater POCD in CPB patients (15), while others found no difference (16, 17). An association between CPB and delirium has yet to be studied and is the main objective of our study.…”

Section: Introductionmentioning

confidence: 97%

Risk factors for delirium after cardiac surgery: a historical cohort study outlining the influence of cardiopulmonary bypass

O’Neal

Billings

Liu

et al. 2017

Can J Anesth/J Can Anesth

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Purpose Cardiopulmonary bypass (CPB) induces a significant inflammatory response that may increase the risk for delirium. We hypothesized that exposure to CPB during coronary artery bypass grafting surgery would correlate with an increased risk of delirium and would be associated with several other outcomes. Methods We reviewed clinical data from two databases at our medical center, the Cardiac Surgery Perioperative Outcomes Database and the Society of Thoracic Surgeons Database. Patients undergoing elective coronary artery bypass grafting surgery (on-pump and off-pump) from November 1, 2009 to September 30, 2015 were included in the study. Delirium was defined as any positive CAM-ICU exam following surgery during the ICU course. We performed logistic regression to isolate the association between CPB exposure and delirium adjusted for predetermined risk factors and potential confounders. Results During the study period, a total of 2,280 patients underwent elective coronary artery bypass grafting surgery with 384 patients (16.9%) exposed to CPB. Delirium was diagnosed in 451 patients (19.8%). CPB exposure demonstrated a significant independent association with delirium (P = 0.002). The adjusted relative risk (RR) of delirium was 2.18 (95% CI, 1.39 to 3.07; P = 0.002) among patients exposed to CPB for 142 minutes (90th percentile of CPB duration), compared to a RR of only 1.51 (95% CI, 0.92 to 2.29; P = 0.10) for those on CPB for 54 minutes (10th percentile). Conclusions CPB use and duration of use were associated with an increased risk of delirium in patients undergoing coronary artery bypass grafting surgery.

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Early neuropsychological dysfunction in elderly high-risk patients after on-pump and off-pump coronary bypass surgery

Abstract: Off-pump CABG reduced postoperative NP dysfunction in elderly patients with severe systemic atherosclerosis compared to on-pump CABG.

Cited by 18 publications

References 31 publications

Associations of dyslipidaemia and lipid-lowering treatment with risk of postoperative cognitive dysfunction: a systematic review and meta-analysis

Associations of dyslipidaemia and lipid-lowering treatment with risk of postoperative cognitive dysfunction: a systematic review and meta-analysis

Off-Pump Coronary Artery Bypass Grafting Revisited: Experience and Evidence from Japan

Risk factors for delirium after cardiac surgery: a historical cohort study outlining the influence of cardiopulmonary bypass

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