Early Methylglyoxal Exposure Leads to Worsened Cardiovascular Function in Young Rats
Marcos Divino Ferreira-Junior,
Keilah Valéria N. Cavalcante,
Jaqueline M. Costa
et al.
Abstract:Background: Though maternal diabetes effects are well described in the literature, the effects of maternal diabetes in postnatal phases are often overlooked. Diabetic individuals have higher levels of circulating glycotoxins, and there is a positive correlation between maternal-derived glycotoxins and circulating glycotoxins in their progeny. Previous studies evaluated the metabolic effects of high glycotoxin exposure during lactation in adult animals. However, here we focus on the cardiovascular system of juv… Show more
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