Early medical and surgical treatment of cryptorchidism: clinical, anatomic, and histologic findings

Lala, Roberto; Sanctis, C. De; Canavese, F; Bardini, T; Hadžiselimović, Faruk

doi:10.1007/bf00176596

Cited by 13 publications

(7 citation statements)

References 6 publications

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“…Some authors have shown that a better histology at surgery (total germ cell count and the presence of Ad spermatogonia) could be an indicator of better fertility [5,6] . Similarly, we obtained better results using hormonal therapy before surgery in the fi rst year of life [11,12] . Whether these hypotheses could be confi rmed after puberty remained an open question.…”

Section: Introductionmentioning

confidence: 52%

Sperm Count of Young Men Surgically Treated for Cryptorchidism in the First and Second Year of Life: Fertility is Better in Children Treated at a Younger Age

et al. 2009

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Section: Introductionmentioning

confidence: 52%

Sperm Count of Young Men Surgically Treated for Cryptorchidism in the First and Second Year of Life: Fertility is Better in Children Treated at a Younger Age

et al. 2009

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“…In the same study, low birth weight was pointed to as a risk factor for testicular maldescent. The association of infertility with maldescended testes is still controversial [25]; nevertheless, several reports in the literature have demonstrated a relationship between infertility, with previous history of cryptorchidism [2,6,32,351. Recent studies [8,30,401 report increasing incidence of cryptorchidism, which also would increase the risk for infertility and testicular cancer [ 1 1, 18, 341.…”

mentioning

confidence: 99%

“…Some authors have advocated surgery as the first therapeutic alternative [26, 381; for others, hormonal treatment should precede surgery [19,20,321. There is general consent that the cryptorchid testis should be treated as early as possible to avoid structural changes in the gonad tissue [32,37,411. In some reports, it has been recommended that hormonal therapy be initiated before 2 years of age [19,20,321; in others it has been recommended that therapy be initiated at ages between 3 and 4 years [3][4][5]291.…”

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confidence: 99%

Cryptorchidism: Treatment with Human Chorionic Gonadotropin—a Venezuelan Experience

et al. 1997

Archives of Andrology

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“…In consideration of the fact that early correction is required, other surgical options should be approached critically [6,29,30]. Alternatives and new therapeutic approaches with the aim of improving the viability and function of the testis are being investigated.…”

Section: Discussionmentioning

confidence: 99%

Neovascularisation of the testes by experimental omentotesticulopexy

Lobl

Frigo

Beer

et al. 2000

Pediatric Surgery International

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With the currently used surgical procedures, surgical correction of extreme forms of high undescended testes is associated with an atrophy rate of 10% to 30%. In this experimental study in two groups of Sprague-Dawley rats of pubescent age, we examined whether fixation (pexy) of an omental flap on the testis (omentotesticulopexy = OMTX) permits preservation of the viability of the parenchyma. A left-sided OMTX was performed in group 1 with the animals under general anaesthesia. An omental flap was prepared. The tunica albuginea of the testis planned for OMTX was pierced with a needle (26 x 23 G) within an area with a diameter of 1 cm; a puncture distance of 2 mm was used. The omental flap was then fixed using absorbable monofilament 6-0 interrupted sutures. Six weeks later the spermatic vessel was transected at this site. The right testis was left untouched throughout the procedure; it remained in situ. In group 2 only the spermatic vessel on the left side was severed. The right testis was not manipulated and remained in situ. After a total of 10 weeks both testes were removed from all rats and fixed in formalin. Standardised haematoxylin and eosin staining was performed and histological sections were obtained. The size of the testicles, Leydig-cell count, viability, and calcified areas within the tissue were determined for all testicles. Student's t-test was used for statistical evaluation. The study showed that OMTX leads to neovascularisation in the area of fixation and that viability can be preserved within this area.

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Early medical and surgical treatment of cryptorchidism: clinical, anatomic, and histologic findings

Cited by 13 publications

References 6 publications

Sperm Count of Young Men Surgically Treated for Cryptorchidism in the First and Second Year of Life: Fertility is Better in Children Treated at a Younger Age

Sperm Count of Young Men Surgically Treated for Cryptorchidism in the First and Second Year of Life: Fertility is Better in Children Treated at a Younger Age

Cryptorchidism: Treatment with Human Chorionic Gonadotropin—a Venezuelan Experience

Neovascularisation of the testes by experimental omentotesticulopexy

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