Early Local Recurrence of a Pure Embryonal Rhabdomyosarcoma of the Testis Successfully Managed with Local Resection Associated with Lymphadenectomy and Adjuvant Chemotherapy

Ahsaini, Mustapha; Kassogue, Amadou; Tazi, Mohammed Fadl; Idrissi, Karima; Moumna, Kaoutar; Chbani, Laïla; Mellas, Soufiane; Ammari, Jallal Eddine; Khallouk, Abdelhak; Amarti, Afaf; Fassi, Mohammed Jamal El; Farih, Moulay Hassan

doi:10.1007/s12558-014-0309-2

Cited by 4 publications

(3 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…3 Existe controversia en la necesidad de practicar una linfadenectomía sistemática pues se sabe que 19-38% de los tumores tienen afectación de ganglios linfáticos al momento del diagnóstico, aunque puede tener indicación en la citorreducción de nodos, posterior a la quimioterapia. 10,13 Incluso hasta 80% de los pacientes resultan con metástasis. El pronóstico de los pacientes es pobre, con una tasa de recurrencia incluso de 86% y una tasa de supervivencia global de 58 a 65%, específicamente de 68% a 1 año y 30% a 5 años.…”

Section: Discussionunclassified

Rabdomiosarcoma y tumor del saco de Yolk testicular

Murillo¹

2017

Rev Mex Urol

View full text Add to dashboard Cite

ANTECEDENTES: las neoplasias testiculares tienen características morfológicas y manifestaciones clínicas diversas, representan de 1 a 2% de todos los cánceres malignos del hombre y hasta 10% de todas las enfermedades malignas del sistema genitourinario masculino.OBJETIVO: reportar la incidencia, diagnóstico, tratamiento y pronóstico del rabdomiosarcoma testicular y tumor del saco vitelino.CASO CLÍNICO: paciente masculino de 43 años de edad, con padecimiento de ocho meses de evolución caracterizado por aumento de volumen testicular izquierdo, doloroso, de intensidad moderada, irradiado al miembro inferior ipsilateral, con cuadros de remisión y exacerbación, acompañados de dificultad para la ventilación. Se le realizó orquiectomía radical izquierda. El informe histopatológico fue de tumor mixto de células germinales compuesto por tumor de saco vitelino sarcomatoide (50%) y rabdomiosarcoma (30%).CONCLUSIONES: los rabdomiosarcomas intratesticulares son agresivos e infrecuentes. Es común que al momento del diagnóstico los rabdomiosarcomas se manifiesten con afectación ganglionar o metástasis. El estadio clínico, el tipo histológico y el apego al tratamiento influyen en la evolución natural del cáncer.PALABRAS CLAVE: rabdomiosarcoma, saco de Yolk, orquiectomía, testicular.

show abstract

Section: Discussionunclassified

Rabdomiosarcoma y tumor del saco de Yolk testicular

Murillo¹

2017

Rev Mex Urol

View full text Add to dashboard Cite

show abstract

“…1 Paratesticular RMS arises from the mesenchymal elements of the spermatic cord, epididymis or tunica vaginalis. 5 Intratesticular rhabdomyosarcoma is thought to arise either from undifferentiated mesenchyme with a capacity to rhabdomyoblastic differentiation, or from embryonal muscle tissue that has been displaced during the early stages of development. 4 It's also believed to be teratomatous with rhabdomyoblastic overgrowth of…”

Section: Methodsmentioning

confidence: 99%

Primary intratesticular rhabdomyosarcoma: a rare aggressive childhood neoplasm

Kumar

Sethi²,

Maletha

2020

Int J Res Med Sci

View full text Add to dashboard Cite

Testicular tumors are relatively uncommon in children. The tumors of germ cell origin are still frequently encountered. The pure embryonal rhabdomyosarcomas of testis, not associated with sarcomatous component of the germ cell tumor, is a very rare entity. It is a highly aggressive tumor of childhood and young adolescents. In testes, it arises commonly from paratesticular tissue; primary intratesticular being extremely rare. To the best of authors knowledge, only fifteen cases of primary pure intratesticular tumor have been reported in the literature so far. We report a case of eight-year-old child who presented with a progressive painless right testicular enlargement over two months. Ultrasonography showed a heterogenous intratesticular mass. High orchidectomy was performed. Histopathological examination of the specimen assisted with immunohistochemistry revealed embryonal rhabdomyosarcoma.

show abstract

“…Abhijith et al reported that patients aged >10 years, with or without radiographic evidence of retroperitoneal disease, should undergo a staging retroperitoneal lymph node dissection and receive radiation in addition to chemotherapy if the lymph nodes are positive (14). The current tendency is to avoid dissection if the radiological examinations reveal no lymph nodes sized >1 cm (15). RMS is a chemosensitive tumor, and the role of multiagent chemotherapy in its treatment has been clearly demonstrated.…”

Section: B Bmentioning

confidence: 99%

Embryonal rhabdomyosarcoma of the epididymis presenting as epididymitis: A case report

Wang

Liu

Tian

et al. 2016

Molecular and Clinical Oncology

View full text Add to dashboard Cite

Abstract. Paratesticular rhabdomyosarcoma (RMS) is an extremely rare malignancy in adults, accounting for 7% of all RMS cases and 6% of all non-germinal intrascrotal tumors. The clinical signs are similar to those of a hydrocele or testicular tumor, typically presenting as a unilateral, painless mass in the inguinal canal or scrotum. No specific serum markers are currently available for this tumor. RMS of the epididymis is extremely rare. Particularly when it is associated with epididymitis, this malignancy is usually overlooked. We herein present a case of epididymal embryonal RMS, manifesting an painful scrotal edema, misdiagnosed as epididymitis. The patient received 3 cycles of adjuvant chemotherapy postoperatively and remained disease-free after 4 years of follow-up.

show abstract

Early Local Recurrence of a Pure Embryonal Rhabdomyosarcoma of the Testis Successfully Managed with Local Resection Associated with Lymphadenectomy and Adjuvant Chemotherapy

Cited by 4 publications

References 5 publications

Rabdomiosarcoma y tumor del saco de Yolk testicular

Rabdomiosarcoma y tumor del saco de Yolk testicular

Primary intratesticular rhabdomyosarcoma: a rare aggressive childhood neoplasm

Embryonal rhabdomyosarcoma of the epididymis presenting as epididymitis: A case report

Contact Info

Product

Resources

About