Early Life Nutrition and Bone Development in Children

Jones, Graeme

doi:10.1159/000325910

Cited by 25 publications

(31 citation statements)

References 26 publications

(28 reference statements)

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“…Furthermore, in the case of newborns, exclusive breastfeeding during the first months of life should be encouraged, as it has been shown to be a protective factor for bone formation 22. Thus, the calculation of the phase angle used as an auxiliary tool to assess the nutritional status would be important, as the analysis does not depend on anthropometrical parameters, such as weight and height or length, and possibly improved the nutritional status of the patients.…”

Section: Discussionmentioning

confidence: 99%

Phase angle and World Health Organization criteria for the assessment of nutritional status in children with osteogenesis imperfecta

Pileggi

Scalize

Camelo

2016

Revista Paulista de Pediatria (English Edition)

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Objective:To compare the phase angle of patients with osteogenesis imperfecta treated at a tertiary university hospital with patients in a control group of healthy children, and to assess the nutritional status of these patients through the body mass index proposed by the World Health Organization.Methods:Cross-sectional study carried out in a university hospital that included seven patients with osteogenesis imperfecta and a control group of 17 healthy children of the same gender and age. Weight and height were measured and bioelectrical impedance was performed. Subsequently, the phase angle was calculated based on resistance and reactance values.Results:The phase angle of the group of children with osteogenesis imperfecta was significantly lower than that of the control group (p<0.05). The body mass index criterion for age of the World Health Organization showed no difference between groups.Conclusions:Children with osteogenesis imperfecta have a nutritional risk detected by the phase angle, which is a useful tool for nutritional screening. The calculation result could help in the diet therapy of patients with osteogenesis imperfecta.

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Section: Discussionmentioning

confidence: 99%

Phase angle and World Health Organization criteria for the assessment of nutritional status in children with osteogenesis imperfecta

Pileggi

Scalize

Camelo

2016

Revista Paulista de Pediatria (English Edition)

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“…Maternal macronutrient and micronutrient intake during pregnancy has been linked to effects on bone mass in progeny through 6–16 years old [17]. Some have hypothesized that this is due to early programming of later bone responses rather than direct consequence of lower bone mass in the foetus [17]. Maternal smoking, likely acting through compromising uteroplacental function, appears to result in lower bone mass in offspring that resolves by the second decade [17].…”

Section: Introductionmentioning

confidence: 99%

“…While there is some evidence that breastfeeding, compared to replacement feeding, may result in lower bone mass in infancy, other evidence points to better bone mass and lower fracture risk in older children who were breastfed as infants [17]. …”

Section: Introductionmentioning

confidence: 99%

Bone health in children and adolescents with perinatal HIV infection

Puthanakit

Siberry

2013

Journal of the International AIDS Society

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The long-term impact on bone health of lifelong HIV infection and prolonged ART in growing and developing children is not yet known. Measures of bone health in youth must be interpreted in the context of expected developmental and physiologic changes in bone mass, size, density and strength that occur from fetal through adult life. Low bone mineral density (BMD) appears to be common in perinatally HIV-infected youth, especially outside of high-income settings, but data are limited and interpretation complicated by the need for better pediatric norms. The potential negative effects of tenofovir on BMD and bone mass accrual are of particular concern as this drug may be used more widely in younger children. Emphasizing good nutrition, calcium and vitamin D sufficiency, weight-bearing exercise and avoidance of alcohol and smoking are effective and available approaches to maintain and improve bone health in all settings. More data are needed to inform therapies and monitoring for HIV-infected youth with proven bone fragility. While very limited data suggest lack of marked increase in fracture risk for youth with perinatal HIV infection, the looming concern for these children is that they may fail to attain their expected peak bone mass in early adulthood which could increase their risk for fractures and osteoporosis later in adulthood.

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“…). While positive associations between breastfeeding duration and bone properties in children and adolescents born at term have been observed in two studies (Jones ; Molgaard et al . ), there were no such associations in three others (Young et al .…”

Section: Introductionmentioning

confidence: 99%

Is breastfeeding related to bone properties? A longitudinal analysis of associations between breastfeeding duration and pQCT parameters in children and adolescents

Kühn

Kroke

Schönaü

et al. 2012

Maternal & Child Nutrition

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Nutritive and bioactive components of human milk could be involved in programming metabolic systems that affect bone growth throughout the life course. Bone properties in childhood and adolescence might differ, depending on breastfeeding duration. Thus, breastfeeding could be a relevant factor in the context of primary osteoporosis prevention. The prospective association between breastfeeding duration and bone properties was investigated using the data of 284 participants of the Dortmund Nutritional and Anthropometric Longitudinally Designed Study. Breastfeeding duration was assessed during infancy. Bone properties were measured by peripheral quantitative computed tomography (pQCT) at ages 5-23 years. Cortical volumetric bone mineral density, cortical bone mineral content, strength strain index, total cross-sectional area of the bone and cross-sectional area of the cortical bone were determined at the 65% site of the radius. Linear regression analyses were performed to check for differences in pQCT parameters of subjects who had not or shortly been breastfed (0-16 weeks) and subjects who had been breastfed for a long duration (≥17 weeks). Multivariable models adjusted for age, gender, forearm length, muscle cross-sectional area, body mass index standard deviation score (SDS), height SDS and socio-economic status did not yield associations between breastfeeding duration and pQCT parameters. These findings suggest neither protective nor adverse effects of prolonged breastfeeding on bone health in childhood and adolescence. Influences of early nutrition on bone growth might be overridden by current effects of mechanical loads on bone physiology.

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Early Life Nutrition and Bone Development in Children

Cited by 25 publications

References 26 publications

Phase angle and World Health Organization criteria for the assessment of nutritional status in children with osteogenesis imperfecta

Phase angle and World Health Organization criteria for the assessment of nutritional status in children with osteogenesis imperfecta

Bone health in children and adolescents with perinatal HIV infection

Is breastfeeding related to bone properties? A longitudinal analysis of associations between breastfeeding duration and pQCT parameters in children and adolescents

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