Early intensive treatment with statins improves regional longitudinal systolic strain in patients with acute myocardial infarction

The impact of medical therapy on left ventricular strain: Current state and future perspectives

“…96 T A B L E 1 Clinical trials data concerning the impact of medications on myocardial strain significant improvement in regional longitudinal strain in a group of patients receiving intensive rosuvastatin treatment regimen an early after acute myocardial infarction. 100 Moreover, in heart transplant recipient's intensive statin treatment prevented the reduction of GLS. 101 To conclude, in the literature, there is enough convincing data presented about the association between myocardial strain and LV afterload, as well as the possible direct effect of several medication classes on LV strain.…”

“…Statins are widely used in clinical practice as a valuable modifier of cardiovascular risk, although they do not show any direct impact on LV function. However, S. Auscher et al revealed significant improvement in regional longitudinal strain in a group of patients receiving intensive rosuvastatin treatment regimen an early after acute myocardial infarction 100 . Moreover, in heart transplant recipient's intensive statin treatment prevented the reduction of GLS 101 …”