Early hematological and immunological alterations in gasoline station attendants exposed to benzene

Moro, Ângela M.; Brucker, Natália; Charão, Mariele Feiffer; Saüer, Elisa; Freitas, Fernando Monteiro de; Durgante, Juliano; Bubols, Guilherme Borges; Campanharo, Sarah Chagas; Linden, Rafael; Souza, Ana Paula Duarte de; Bonorino, Cristina; Moresco, Rafael Noal; Pilger, Diogo André; Gioda, Adriana; Farsky, Sandra Helena Poliselli; Duschl, Albert; Garcia, Solange Cristina

doi:10.1016/j.envres.2014.11.003

Cited by 34 publications

(22 citation statements)

References 49 publications

(57 reference statements)

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“…There are few reports on the association between environmental contaminant exposure and haematological markers [31–33]. The literature on this specific topic for pregnant women is sparse, however, the limited literature suggests an immunosuppression measured through specific biomarkers in humans exposed to environmental contaminants.…”

Section: Discussionmentioning

confidence: 99%

Persistent organic pollutants and haematological markers in Greenlandic pregnant women: the ACCEPT sub-study

Knudsen

Long

Bonefeld-Jörgensen

2018

International Journal of Circumpolar Health

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The Arctic populations have high blood concentrations of persistent organic pollutants (POPs). Exposure to POPs was related to adverse health effects e.g. immune, neurological and reproductive systems. This study investigates associations between serum POP levels and haematological markers in Greenlandic pregnant women. This cross-sectional study included 189 women enrolled in 2010–2011 at the Greenlandic West coast by the inclusion criteria ≥18 years of age and had lived for 50% or more of their life in Greenland. The associations between the sum of the POP variables polychlorinated biphenyls (sumPCBs), organochlorine pesticides (sumOCPs), perfluoroalkylated substances (sumPFASs) and 24 haematological markers were analysed using linear regression adjusted for age, pre-pregnancy BMI, parity, gestation week, plasma-cotinine and alcohol intake. It showed a significantly inverse association between several haematological markers (eosinophil, lymphocyte, neutrophil and white blood cells) and sumPCBs, sumOCPs and sumPFASs. In addition, the monocyte, mean corpuscular haemoglobin concentration, plateletcrit and platelet count markers were significantly inversely associated with sumPFASs, but the haematocrit and mean erythrocyte corpuscular volume were positively associated with sumPFASs. In conclusion, exposure to POPs influenced several haematological markers, especially cell count parameters, suggesting immunosuppressive potential of POPs in Greenlandic pregnant women. The data need further investigations.

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Section: Discussionmentioning

confidence: 99%

Persistent organic pollutants and haematological markers in Greenlandic pregnant women: the ACCEPT sub-study

Knudsen

Long

Bonefeld-Jörgensen

2018

International Journal of Circumpolar Health

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“…During the extraction, transport, distribution and storage of crude oil and its products, these may be released into the environment in an uncontrolled manner, causing pollution of the atmosphere, lithosphere, hydrosphere and biosphere [1][2][3][4][5][6]. Due to the extent of impact and the adverse effect of oil derivatives on both the inanimate and animate environment, and the limits imposed on their emissions and permissible concentrations in soils and water, the search for effective methods and new materials for the removal of such substances from contaminated sites is extremely important.…”

Section: Introductionmentioning

confidence: 99%

Application of Mineral Sorbents for Removal of Petroleum Substances: A Review

et al. 2017

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Environmental pollution with petroleum products has become a major problem worldwide, and is a consequence of industrial growth. The development of sustainable methods for the removal of petroleum substances and their derivatives from aquatic and terrestrial environments and from air has therefore become extremely important today. Advanced technologies and materials dedicated to this purpose are relatively expensive; sorption methods involving mineral sorbents are therefore popular and are widely described in the scientific literature. Mineral materials are easily available, low-cost, universal adsorbents and have a number of properties that make them suitable for the removal of petroleum substances. This review describes recent works on the use of natural, synthetic and modified mineral adsorbents for the removal of petroleum substances and their derivatives from roads, water and air.

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“…Comparado con estudios de otros países, Amodio-Cocchieri et al (2001) reportan niveles de exposición de 145.4 µg/g CR en la población infantil de un área urbanizada de Italia, mientras que Ruchirawat et al (2006) reportan 170 ± 30 µg/g CR en Tailandia. Nuestros resultados indican que la población infantil de Cadereyta Jiménez está altamente expuesta a benceno, de manera similar a lo que reporta Moro et al (2015) para trabajadores expuestos ocupacionalmente en estaciones de gasolina en Brazil (mediana: 320 µg/g CR).…”

Section: Discussionunclassified

Exposición a Benceno en Una Población Infantil Urbana Del Noreste De México

Ochoa-Martínez

Pelallo-Martínez²,

Ruíz-Vera

et al. 2018

Rev. Int. Contam. Ambie.

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Palabras clave: hidrocarburos, salud infantil, riesgos, Cadereyta Jiménez RESUMEN El objetivo de este estudio fue evaluar el nivel de exposición a benceno en niños del municipio de Cadereyta Jiménez en Nuevo León, a través de la determinación urinaria de ácido trans, trans-mucónico, compuesto utilizado como biomarcador de exposición a benceno. Nuestros resultados indican que el 28 % de la población rebasa el índice biológico de exposición (500 µg/g CR). Debido a que el benceno se relaciona con neoplasias hematológicas, es necesario emprender estudios para evaluar si existen riesgos hematológicos en niños que viven en zonas con actividad petroquímica.Key words: hydrocarbon, health child, risks, Cadereyta Jiménez ABSTRACTThe aim of this study was to assess the benzene exposure levels in children living in Cadereyta Jiménez in Nuevo León state, through determination of urinary trans, transmuconic acid, a biomarker of benzene exposure. Our results shown that 28 % of the population exceeds the biological exposure index (500 µg/g CR). Considering that benzene is related with hematological malignances it is necessary to undertake studies to assess hematological risks in children living in areas with petrochemical activity.

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Early hematological and immunological alterations in gasoline station attendants exposed to benzene

Cited by 34 publications

References 49 publications

Persistent organic pollutants and haematological markers in Greenlandic pregnant women: the ACCEPT sub-study

Persistent organic pollutants and haematological markers in Greenlandic pregnant women: the ACCEPT sub-study

Application of Mineral Sorbents for Removal of Petroleum Substances: A Review

Exposición a Benceno en Una Población Infantil Urbana Del Noreste De México

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