Early goal-directed hemodynamic optimization combined with therapeutic hypothermia in comatose survivors of out-of-hospital cardiac arrest

Gaieski, David F.; Band, Roger A.; Abella, Benjamin S.; Neumar, Robert W.; Fuchs, Barry D.; Kolansky, Daniel M.; Merchant, Raina M.; Carr, Brendan G.; Becker, Lance B.; Maguire, Cheryl; Klair, Amandeep; Hylton, Julie; Goyal, Munish

doi:10.1016/j.resuscitation.2008.12.015

Cited by 269 publications

(145 citation statements)

References 35 publications

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“…1 The study 18 differed from other studies by actively controlling the patients' body temperature during the intervention period and intended to prevent fever during the first 3 days of treatment.…”

Section: Literature Reviewmentioning

confidence: 99%

Caring for Patients Treated With Therapeutic Hypothermia

Mathiesen

McPherson

Ordway

et al. 2015

Critical Care Nurse

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Numerous studies have indicated that therapeutic hypothermia can improve neurological outcomes after cardiac arrest. This treatment has redefined care after resuscitation and offers an aggressive intervention that may mitigate postresuscitation syndrome. Caregivers at Lehigh Valley Health Network, Allentown, Pennsylvania, an academic, community Magnet hospital, treated more than 200 patients with therapeutic hypothermia during an 8-year period. An interprofessional team within the hospital developed, implemented, and refined a clinical practice guideline for therapeutic hypothermia. In their experience, beyond a protocol, 5 critical elements of success (interprofessional stakeholders, coordination of care delivery, education, interprofessional case analysis, and participation in a global database) enhanced translation into clinical practice. (Critical Care Nurse. 2015;35[5]:e1-e13)

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Section: Literature Reviewmentioning

confidence: 99%

Caring for Patients Treated With Therapeutic Hypothermia

Mathiesen

McPherson

Ordway

et al. 2015

Critical Care Nurse

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“…Hypotension is common and is associated with significantly higher mortality and diminished functional status. 31,32 Cerebral autoregulation may be absent or altered in the acute phase after cardiac arrest. A mean arterial pressure of 65 mm Hg or greater should be secured to ensure cerebral and end-organ perfusion.…”

Section: Management Of Post-cardiac Arrest Syndromementioning

confidence: 99%

“…Trzeciak et al, 31 Gaieski et al, 32 Sundgreen et al 33 Buunk et al, 35 Bisschops et al, 36 Kilgannon et al, 37 Diringer 38 Hachimi-Idrissi et al, 24 Bernard et al, 25 HACA, 26 Sundgreen et al 33 Finfer et al, 42 Cueni-Villoz et al 43 Laurent et al 34 Dumas et al, 39 O'Connor et al 41 …”

Section: Referencesmentioning

confidence: 99%

From Door to Recovery: A Collaborative Approach to the Development of a Post–Cardiac Arrest Center

Williams

Calder²,

Cocchi³

et al. 2013

Critical Care Nurse

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Out-of-hospital cardiac arrest remains common and, despite advances in resuscitation practices, continues to carry a high mortality that may be influenced by several factors, including where a patient is cared for after the cardiac arrest. Implementing a post–cardiac arrest care guideline for survivors of out-of-hospital and in-hospital cardiac arrest involves a multidisciplinary approach with short-term and long-term strategies. Physician and nursing leaders must work in synergy to guide the implementation of an evidence-based plan of care. A collaborative approach was used at a hospital to develop processes, build consensus for protocols, and provide support to staff and teams. A joint approach has allowed the hospital to move from traditional silos of individual departmental care to a continuum of patient-focused management after cardiac arrest. This care coordination is initiated in the emergency department and follows the patient through to discharge.

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“…For instance, Gaieski et al 113 demonstrated successful implementation of a post-cardiac arrest protocol that focused on early goal-directed hemodynamic optimization and TH. In addition, Sunde et al 114 implemented a post-cardiac arrest strategy that included control of hemodynamics, TH, and PCI that resulted in significantly improved survival and neurological status.…”

Section: Post-cardiac Arrest Carementioning

confidence: 99%