Early Efficacy and Complications of Releasable Sutures for Trabeculectomy in Primary Angle-closure Glaucoma

Liang, Yuan Bo; Feng, Mengyu; Meng, Hai Lin; Fan, Su Jie; Wang, Xing; Xie, Li L.; Peng, Yi; Tang, Xin; Wang, Ning L.; Thomas, Ravi

doi:10.1097/ijg.0b013e31826981c9

Cited by 15 publications

(11 citation statements)

References 12 publications

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“…57,68,69 We also observed that daytime fluctuations in PACG after trabeculectomy, 3.8 ± 2.1 mm Hg 70 was lower than that reported after LPI, 5.44 ± 2.4 mm Hg. 71 Increased use of trabeculectomy may be suggested in the management of both PACG and POAG.…”

Section: Complications Of Initial Lpi and Trabeculectomycontrasting

confidence: 72%

“…60,61 In addition, the surgery impairs visual acuity during the early phase in about 20% of the patients. 57,62 PRIMARY TRABECULECTOMY There are limited data for primary trabeculectomy in PACG compared with LPI, but there are some welldesigned studies that reported the results of trabeculectomy as an initial treatment in POAG patients. We can only attempt to extrapolate this to PACG.…”

Section: Complications Of Initial Lpi and Trabeculectomymentioning

confidence: 98%

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Initial Treatment for Primary Angle-Closure Glaucoma in China

Liang

Wang

Rong

et al. 2015

Journal of Glaucoma

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China has a large burden of primary angle-closure glaucoma (PACG) and the approach to treatment is different from that in most parts of the world. In China, trabeculectomy is a mainstay of initial treatment for PACG and laser peripheral iridotomy is reserved for PAC and PACG with peripheral angle synechiae ≤180 degrees. The greater reduction of and more stable IOP, lower frequency of acute angle closure, decreased progression of peripheral anterior synechia and glaucoma, and the reduction of ocular complications associated with long-term use of glaucoma medications support the use of initial trabeculectomy in PACG without significant lens opacities. Further study is required to determine the indications and effectiveness of initial trabeculectomy for PACG in a developing country setting.

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Section: Complications Of Initial Lpi and Trabeculectomycontrasting

confidence: 72%

Section: Complications Of Initial Lpi and Trabeculectomymentioning

confidence: 98%

Initial Treatment for Primary Angle-Closure Glaucoma in China

Liang

Wang

Rong

et al. 2015

Journal of Glaucoma

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“…Although this procedure is very effective in reducing intraocular pressure (IOP) in the short term, surgical failure has often been observed over time[5, 6]. Additionally, trabeculectomy is associated with a high incidence of early and late postoperative complications[7–10], therefore, an alternative to trabeculectomy for treating glaucoma is urgently required.…”

Section: Introductionmentioning

confidence: 99%

Comparison of Ahmed Glaucoma Valve Implantation and Trabeculectomy for Glaucoma: A Systematic Review and Meta-Analysis

et al. 2015

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ObjectiveTo compare the efficacy and safety of Ahmed glaucoma valve implantation (AGV) with trabeculectomy in the management of glaucoma patients.MethodsA comprehensive literature search (PubMed, Embase, Google, and the Cochrane library) was performed, including a systematic review with meta-analysis of controlled clinical trials comparing AGV versus trabeculectomy. Efficacy estimates were the weighted mean differences (WMDs) for the percentage intraocular pressure reduction (IOPR %) from baseline to end-point, the reduction in glaucoma medications, and the odds ratios (ORs) for complete and qualified success rates. Safety estimates were the relative risks (RRs) for adverse events. All outcomes were reported with a 95% confidence interval (CI). Statistical analysis was performed using the RevMan 5.0 software.ResultsSix controlled clinical trials were included in this meta-analysis. There was no significant difference between the AGV and trabeculectomy in the IOPR% (WMD = -3.04, 95% CI: -8.36- 2.26; P = 0.26). The pooled ORs comparing AGV with trabeculectomy were 0.46 (0.22, 0.99) for the complete success rate (P = 0.05) and 0.97 (0.78–1.20) for the quantified success rate (P = 0.76). No significant difference in the reduction in glaucoma medicines was observed (WMD = 0.24; 95% CI: -0.27–0.76; P = 0.35). AGV was found to be associated with a significantly lower frequency of all adverse events (RR = 0.71; 95%CI: 1.14–0.97; p = 0.001) than trabeculectomy, while the most common complications did not differ significantly (all p> 0.05).ConclusionAGV was equivalent to trabeculectomy in reducing the IOP, the number of glaucoma medications, success rates, and rates of the most common complications. However, AGV was associated with a significantly lower frequency of overall adverse events.

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“…En relación con el uso de suturas liberables en la trabeculectomía de ojos con GCAP, Liang et al realizaron un estudio prospectivo y aleatorizado incluyendo a 87 pacientes en el grupo de trabeculectomía estándar y 88 en el grupo de suturas liberables (dos permanentes y dos liberables) 89 . La eficacia hipotensora ocular a los 3 meses fue similar con ambos procedimientos.…”

Section: Tratamiento Quirúrgicounclassified

“…La eficacia hipotensora ocular a los 3 meses fue similar con ambos procedimientos. La hipotonía transitoria fue observada más frecuentemente en el grupo de suturas fijas (20,4% vs 9,1%), no encontrándose diferencias significativas en la incidencia del resto de complicaciones 89 .…”

Section: Tratamiento Quirúrgicounclassified