Early effects of transcatheter aortic valve implantation and aortic valve replacement on myocardial function and aortic valve hemodynamics: Insights from cardiovascular magnetic resonance imaging

Abstract

There was no significant difference in early left ventricular systolic function between techniques. Whereas right ventricle systolic function was preserved in the AVR group, it was significantly impaired early after TAVI, possibly reflecting a clinically important pathophysiologic consequence of paravalvular aortic regurgitation.

Acute Reverse Remodelling After Transcatheter Aortic Valve Implantation: A Link Between Myocardial Fibrosis and Left Ventricular Mass Regression

“…This suggests that those with fibrosis may have greater wall stress, with stiffer, less compliant left ventricles leading to elevated filling pressures but not necessarily greater hypertrophy. There was no overall acute change in LVEF which is in keeping with other CMR studies [16], however, those with a reduced baseline LVEF did derive a significant improvement, suggesting that acute afterload reduction does have a favourable effect on LVEF in those with an abnormality at baseline.…”

Meta-analysis of right ventricular function in patients with aortic stenosis after transfemoral aortic valve replacement or surgical aortic valve replacement

“…Finally, 11 studies met the inclusion criteria and were included in this meta-analysis ( Figure 1). 12,[16][17][18][19][20][21][22][23][24][25] The search for the meta-analysis was performed on February 14, 2020. Study descriptions and patient characteristics are summarized in Tables 1 and 2 as well as Supplemental Tables 1 and 2 online.…”

Comprehensive Right-Sided Assessment for Transcatheter Aortic Valve Replacement Risk Stratification: Time for a Change

“…30,31 However, changes in RV systolic function do not seem to be uniform, as worsening of RV systolic function after TAVR, assessed by cardiac magnetic resonance, also has been reported. 32 Advanced imaging methods such as speckle-tracking strain imaging, 28,33 three-dimensional echocardiography, 34 computed tomography, and cardiac magnetic resonance 35 complement 2D echocardiography and invasive hemodynamic testing by providing useful surrogate end points for disease progression and may help track response to interventions for future clinical trials in PH.…”