2021
DOI: 10.1038/s41433-021-01718-4
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Early DMO: a predictor of poor outcomes following cataract surgery in diabetic patients. The DICAT-II study

Abstract: Background The prospective DIabetes and CATaract Study II (DICAT II) was performed to characterise the risks of cataract surgery to the retinae of patients with early diabetic macular oedema (E-DMO). Methods DICAT II was a prospective, comparative, multicentre, observational study involving six Italian clinics. Patients were aged ≥55 years, had type 1 or 2 diabetes with spectral-domain optical coherence tomography evidence of ESASO classification Early DMO. Group 1 eyes… Show more

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Cited by 5 publications
(3 citation statements)
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References 18 publications
(27 reference statements)
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“…[ 22 ] As reported previously, the predictors of poor outcomes of DME following cataract surgery in patients with diabetes include early DME; hypertension; and the aqueous levels of VEGF, interleukin-6, and proteins. [ 23 , 24 ] The most severe aspect of DME is attributed to 2 parameters. First, the disruption of retinal tissue caused by retinal edema is not reversible.…”
Section: Discussionmentioning
confidence: 99%
“…[ 22 ] As reported previously, the predictors of poor outcomes of DME following cataract surgery in patients with diabetes include early DME; hypertension; and the aqueous levels of VEGF, interleukin-6, and proteins. [ 23 , 24 ] The most severe aspect of DME is attributed to 2 parameters. First, the disruption of retinal tissue caused by retinal edema is not reversible.…”
Section: Discussionmentioning
confidence: 99%
“…While the ESASO Classification has already provided valuable descriptive insights on DME [ 5 , 6 , 14 ], its clinical relevance required further validation. To address this knowledge gap, the objective of this retrospective multicenter study was to assess the therapeutic response to intravitreal agents in eyes at different stages of DME progression.…”
Section: Introductionmentioning
confidence: 99%
“…14 Early DME is a poor prognostic factor after cataract surgery, and close pre- and postoperative monitoring has been advocated in eyes with early DME. 15 Finally, OCT allows quantitative measurements of the choroid. Diabetic eyes have choroidal depletion that matches DR severity; moreover, eyes with DME tend to have a higher lumen-to-stroma ratio in the macula than eyes without DME.…”
mentioning
confidence: 99%