Early detection of viral DNA in breast cancer using fingered aluminium interdigitated electrode modified by Streptavidin-biotin tetravalent complex

Ghosh, Arnab; Gopinath, Subash C. B.; Firdous, Sayeed Mohammad; Ramanathan, Santheraleka

doi:10.1016/j.jics.2022.100604

Cited by 4 publications

(1 citation statement)

References 22 publications

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“…The application of this system based on biotin-streptavidin interaction is widely distributed in the field of biosensors not only for the immobilization of antibodies but also, for example, in the electrochemical detection of proteases as biomarkers, which are an important therapeutic target in different diseases [ 15 ], in the detection of human papillomavirus [ 16 ], or in the biofunctionalization of quantum dots to detect dengue markers [ 17 ]. Also, among the most recent biosensors that have used this system is the detection of viral DNA in breast cancer [ 18 ] or of salmonella bacteria in milk [ 19 ].…”

Section: Introductionmentioning

confidence: 99%

Reports on the sensitivity enhancement in interferometric based biosensors by biotin-streptavidin system

Murillo,

Holgado,

Laguna

2023

Heliyon

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Section: Introductionmentioning

confidence: 99%

Reports on the sensitivity enhancement in interferometric based biosensors by biotin-streptavidin system

Murillo,

Holgado,

Laguna

2023

Heliyon

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Gold nanourchin on multiple‐point dielectrode for glucose biosensing by current‐potential measurement

Chen,

Huang,

Zhou

2024

Biotech and App Biochem

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Gestational diabetes (GD) is a condition characterized by elevated blood sugar levels during pregnancy. GD poses various health risks, such as serious birth injuries, the need for cesarean delivery, and the necessity of newborn care. Monitoring glucose levels is essential for ensuring safe delivery and reducing the risks to both the mother and fetus. Various sensors are readily available for monitoring glucose levels, and researchers are continually working to develop highly sensitive glucose sensors. This research aimed to develop a gold nanourchin (AuNU)‐hybrid biosensor for quantifying glucose on a multi‐point electrode sensor. Glucose oxidase (GOx) was attached to the AuNU and seeded on the sensing surface using an amine linker. The current‐potential (1–2 V at 0.1 V sweep) was recorded for the GOx–glucose interaction, with a limit of detection of 560 μM and a regression coefficient (R2) of 0.9743 [y = 0.9106x − 0.9953] on the linear curve. The sensitivity was estimated to be 3.5 mAcm−2M−1. Furthermore, control experiments with galactose, sucrose, and fructose did not yield an increase in current‐potential, confirming specific glucose detection. This experiment helps in monitoring glucose levels to manage conditions associated with GD.

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Gold-antibody-aptamer complexed electrochemical sensing surface for septic arthritis biomarker determination

Yang,

Tian,

2024

Heliyon

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Early detection of viral DNA in breast cancer using fingered aluminium interdigitated electrode modified by Streptavidin-biotin tetravalent complex

Cited by 4 publications

References 22 publications

Reports on the sensitivity enhancement in interferometric based biosensors by biotin-streptavidin system

Reports on the sensitivity enhancement in interferometric based biosensors by biotin-streptavidin system

Gold nanourchin on multiple‐point dielectrode for glucose biosensing by current‐potential measurement

Gold-antibody-aptamer complexed electrochemical sensing surface for septic arthritis biomarker determination

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